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  • 11
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    International Journal of Quantum Chemistry 38 (1990), S. 461-486 
    ISSN: 0020-7608
    Keywords: Computational Chemistry and Molecular Modeling ; Atomic, Molecular and Optical Physics
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: This study is a unified approach to quantum theories of polyacen carcinogenesis. Part I discusses the M, L, and B regions theory. Although the M region of polyacens is much less reactive than is the K region, the chemical reactivity of these two regions parallels each other. Consequently, the K-L Pullman's theory may be reformulated by replacing the K region by the M region. The M-L regions theory improves all the quantum structure-carcinogenic activity relationships obtained previously in the K-L framework. Moreover, it would appear that in these correlations, the most important role is played by nonconcerted electrophilic reactions. We suggest that the M-L modified Pullman's theory and the Bay (B) region theory, proposed by Jerina et al., are related to different steps of the metabolic activation mechanism leading to ultimate carcinogen: the first step for the Pullman's theory and the carbocation step for the theory of the Bay region. We have termed the “M, L and B regions theory” as this unified approach to the problem of polyacens carcinogenesis.
    Additional Material: 8 Ill.
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  • 12
    ISSN: 0020-7608
    Keywords: Computational Chemistry and Molecular Modeling ; Atomic, Molecular and Optical Physics
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: This study is a unified approach to quantum theories of polyacen carcinogenesis. Part II is on the role of the K-region in metabolic activation process leading to ultimate carcinogen and discusses the M, L, and BK theory. The saturation of the polyacen K-region, or the transformation into a quinoid one, deactivates the carcinogenic process going through a diol epoxyde, which results in Bay-region carbocation. K and B regions must be considered as two interdependent parts of the same structural entity, which may be termed the BK-region. The M, L, and BK theory achieves a complete unification of the Pullman and Jerina and other theories.
    Additional Material: 3 Ill.
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  • 13
    ISSN: 0170-2041
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Eine einfache Synthese von substituierten Perhydro-1,3-thiazin-4-onen und 2-Thioxoperhydro-4-pyrimidinonenDie basisch katalysierte Cyclisierung der N-Propenoylthioharnstoffe 3 liefert je nach den Reaktionsbedingungen entweder 2,6-disubstituierte 2,3,5,6-Tetrahydro-4H-1,3-thiazin-4-one 4 oder 1,6-disubstituierte 2-Thiouracile 5. Unter denselben Reaktionsbedingungen können die Verbindungen 5 durch eine Art Dimroth-Umlagerung aus den 1,3-Thiazin-4-onen 4 erhalten werden.
    Notes: Depending on the reaction conditions either 2,6-disubstituted 2,3,5,6-tetrahydro-4H-1,3-thiazin-4-ones 4 or 1,6-disubstituted 2-thiouracils 5 are readily prepared by base-catalyzed cyclization of N-propenoylthioureas 3. Compounds 5 could also be obtained by Dimroth-type rearrangement of 1,3-thiazin-4-ones 4 under the same reaction conditions.
    Additional Material: 2 Tab.
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  • 14
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Liebigs Annalen 1990 (1990), S. 293-296 
    ISSN: 0170-2041
    Keywords: Pyridazine, derivatives ; Pyrazolo-pyridazine, derivative ; Pyrido-pyridazine, derivative ; Isoxazolo-pyridazine, derivative ; Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The pyridazines 3, 4, 5, and 7 were obtained by reaction of the hydrazone derivatives 2 with several reagents. By treatment of 5 with acetic acid/hydrochloric acid, the pyrazolo[4,3-c]-pyridazine 6 was formed. The pyrido-pyridazine derivatives 8 and 9 were obtained by reaction of 2 and 3 with malononitrile and ethyl cyanoacetate, respectively, and the isoxazolo-pyridazines 11 by reaction of 3a, b with hydroxylamine hydrochloride in ethanolic sodium ethoxide solution. The intermediate 9 was separated by reaction of 3a, b with hydroxylamine hydrochloride in ethanolic sodium acetate solution.
    Additional Material: 2 Tab.
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  • 15
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Liebigs Annalen 1990 (1990), S. 461-464 
    ISSN: 0170-2041
    Keywords: Antitumor agents ; Oxaziridines ; Aldimines, unsaturated ; Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: A convenient method for the synthesis of previously unknown oxaziridines having unsaturated substituents at the 3-position (3a-k) is based on the selective oxidation of the imino group of α,β-unsaturated aldimines 2 with m-chloroperbenzoic acid. The title compounds and 2-tert-butyl-3-(phenylethynyl)oxaziridine (3k) exhibit potent activity against experimental tumor cells in vitro.
    Additional Material: 4 Tab.
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  • 16
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Fire and Materials 18 (1994), S. 9-16 
    ISSN: 0308-0501
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Architecture, Civil Engineering, Surveying , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Burn tests were conducted on a number of Christmas trees commonly used in typical households. Trees were kept in room conditions for several weeks to dry out. Burn tests were also conducted on fresh and almost fresh trees to compare their burning behaviors wilth those of dry trees. Two trees were moistened and wetted prior to burn to observe the effects of water on burning of dry trees. The foremost objective of this work was to quantitatively demonstrate the potential fire hazard of Christmas trees by measuring the rate of heat release and room temperature during the burn.
    Additional Material: 13 Ill.
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  • 17
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Electrophoresis 16 (1995), S. 1295-1300 
    ISSN: 0173-0835
    Keywords: Triticum ; Secale ; Hordeum ; Two-dimensional polyacrylamide gel electrophoresis ; Phylogenetic relationships ; Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Two-dimensional gel electrophoresis of shoot proteins was used to study the relationships between Triticum, Secal, and Hordeum. A high level of polymorphism was found among the 1275 spots scored: only 198 spots were found common to all. But, under the hypothesis that only allelic variations were observed, the mean number of alleles per locus was only two. Phenograms were built from different distance indices. All of them showed Triticum genomes A and D close to each other, Hordeum, far from the Triticum cluster, and Secale at an intermediate position. A discussion on the use of various distance indices is presented.
    Additional Material: 3 Ill.
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  • 18
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Fire and Materials 16 (1992), S. 159-167 
    ISSN: 0308-0501
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Architecture, Civil Engineering, Surveying , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: An investigation has been carried out of the limiting oxygen index (LOI) test. A review of the literature shows that, although there is abundant information on the test, it is not clear that its results correlate well with those of any other test, or indeed with those of real fires. Theoretical considerations indicate that the test could be improved by using it with bottom ignition rather than with the standard top ignition. A number of materials were tested in the cone calorimeter and in the LOI, and various correlations were attempted. In general, correlations between some of the cone calorimeter properties measured and the inverse of the LOI made sense. These correlations were not, however, sufficiently sensitive, even when investigating small effects on a single base polymer system, to justify using the LOI as a proxy for the cone in any way. The LOI is likely to continue to be used extensively. This work suggests that quality control and, possibly, mechanistic or other flame-retardant additive studies, are its only applications where the results can be justified.
    Additional Material: 9 Ill.
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  • 19
    Electronic Resource
    Electronic Resource
    Brookfield, Conn. : Wiley-Blackwell
    Journal of Vinyl and Additive Technology 15 (1993), S. 17-21 
    ISSN: 0193-7197
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Process Engineering, Biotechnology, Nutrition Technology
    Notes: This study seeks to substitute fumed silica for chlorinated polyethylene (CPE) within a rigid PVC formulation intended for profile extrusion such as doors and window frames. The effect of fumed silica on both mechanical (tensile and impact) and thermal (Vicat point, HDT, and linear thermal expansion coefficient) properties were investigated. Five rigid PVC formulations were prepared, including a reference one (F1), then F1 with CPE, F1 with untreated silica, F1 with heat treated silica, and finally F1 with dried silica and a coupling agent. The effect of CPE on mechanical properties was very modest. On the other hand, CPE showed its inefficiency, in that HDT and Vicat point were decreased. Heat treated silica showed the greatest improvement in both mechanical and thermal properties. Untreated silica showed a small effect on both properties. Finally, the incorporation of coupling agent gave considerable improvement in both mechanical and thermal properties.
    Additional Material: 8 Ill.
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  • 20
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Acta Polymerica 40 (1989), S. 708-710 
    ISSN: 0323-7648
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Description / Table of Contents: Die durch Cerionen initiierte Pfropfung von Methylmethacrylat auf Stärke wurde untersucht, wobei die nicht absorbierten Cerionen entweder im Substrat blieben oder entfernt wurden. Der Pfropfgrad, die Molekülmasse der gepfropften Ketten und die Anzahl der Pfropfungen wurden in Abhängigkeit von der Konzentration der Cerionen bestimmt. Auf Basis der erhaltenen Ergebnisse wird der Mechanismus der Pfropfreaktion diskutiert.
    Notes: Methyl methacrylate was grafted onto starch by the ceric ion method with and without removing of the unabsorbed ceric ions. Graft level, molecular weight of the grafted chains, and number of the grafted chains were measured in dependence on ceric ion concentration. On base of the results the mechanism of the grafting reaction is discussed.
    Additional Material: 2 Ill.
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