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  • 11
    Electronic Resource
    Electronic Resource
    A rollercoaster ride (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 284-284 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] If only we knew then, what we know now. Biotech investing has changed over the past ten years in two major ways. First, thanks to fitful bursts of initial public offerings (IPOs), the growth and sheer diversity of companies listed on exchanges has greatly expanded the choices available to ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0306-284
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  • 12
    Electronic Resource
    Electronic Resource
    When your stock takes a nosedive (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 144-144 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] You've done your homework, studied a company's drugs in development and on the market, assessed the risks, checked its finances and arrived at an investment thesis. You estimate good potential returns and buy happily. But later, the stock drops significantly—perhaps 20%. Although you know you ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0206-144
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  • 13
    Electronic Resource
    Electronic Resource
    Trials and error (2005)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 23 (2005), S. 1481-1481 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Biotech drugmaker stock prices are volatile not just at quarterly earnings time, but throughout the heavily regulated drug development process. Early signs of a drug's success or failure can dramatically change investment potential versus risk, so intelligent investing requires deep knowledge of ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt1205-1481
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  • 14
    Electronic Resource
    Electronic Resource
    The number on biotech indexes (2005)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 23 (2005), S. 1356-1356 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Those of us who invest in stocks can repeat the major indexes of market performance in our sleep because they are ubiquitous in the financial media. The S&P, FTSE, CAC, DAX and Nikkei are acronyms known worldwide for their alleged measure of the US, UK, French, German and Japanese stock ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt1105-1356
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  • 15
    Electronic Resource
    Electronic Resource
    Time to kick that drug habit (2005)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 23 (2005), S. 23-23 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Drugmaking or diagnostics? Biotech investors know that the former snares headlines, venture capital, initial public offerings and investor passion, whereas the latter produces slumber. A former star-quality CEO of a product-less and profitless biopharmaceutical firm once sniffed to me that one ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0105-23
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  • 16
    Electronic Resource
    Electronic Resource
    The Ten Commandments for biotech investors (2007)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 25 (2007), S. 44-44 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Over five years, I've written in these pages on almost every facet of biotech investing. But I've been remiss: never before have I brought together all those precepts in one place. Therefore, as a parting thought—my column in this issue will (unhappily) be my last for Nature Biotechnology ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0107-44
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  • 17
    Electronic Resource
    Electronic Resource
    Gene regulation through nuclear organization (2007)
    [s.l.] : Nature Publishing Group
    Nature structural & molecular biology 14 (2007), S. 1049-1055 
    Details
    ISSN: 1545-9985
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] The nucleus is a highly heterogeneous structure, containing various 'landmarks' such as the nuclear envelope and regions of euchromatin or dense heterochromatin. At a morphological level, regions of the genome that are permissive or repressive to gene expression have been associated with these ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nsmb1324
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  • 18
    Electronic Resource
    Electronic Resource
    Is one solution good enough? (2006)
    [s.l.] : Nature Publishing Group
    Nature structural & molecular biology 13 (2006), S. 184-185 
    Details
    ISSN: 1545-9985
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] To the Editor: Three-dimensional structures of proteins, nucleic acids and other macromolecules are central to understanding biology. They provide a basis for understanding catalytic mechanisms, ligand binding and interactions in multi-component assemblies. Macromolecular structures are essential ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nsmb0306-184
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  • 19
    Electronic Resource
    Electronic Resource
    Mapping the interaction surface of linker histone H1 0 with the nucleosome of native chromatin in vivo (2006)
    [s.l.] : Nature Publishing Group
    Nature structural & molecular biology 13 (2006), S. 250-255 
    Details
    ISSN: 1545-9985
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] H1 linker histones stabilize the nucleosome, limit nucleosome mobility and facilitate the condensation of metazoan chromatin. Here, we have combined systematic mutagenesis, measurement of in vivo binding by photobleaching microscopy, and structural modeling to determine the binding geometry of the ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nsmb1050
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  • 20
    Electronic Resource
    Electronic Resource
    Structural definition of the F-actin–binding THATCH domain from HIP1R (2006)
    [s.l.] : Nature Publishing Group
    Nature structural & molecular biology 13 (2006), S. 121-130 
    Details
    ISSN: 1545-9985
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] Huntingtin-interacting protein-1 related (HIP1R) has a crucial protein-trafficking role, mediating associations between actin and clathrin-coated structures at the plasma membrane and trans-Golgi network. Here, we characterize the F-actin–binding region of HIP1R, termed the talin-HIP1/R/Sla2p ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nsmb1043
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