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  • 1995-1999  (40)
  • 1965-1969  (21)
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  • 11
    ISSN: 1432-0827
    Keywords: Key words: Bone metabolic markers — Predictor — Osteoporosis — Epidemiology — Bone mineral density.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Abstract. The purpose of this study was to ascertain whether biochemical markers of bone turnover predict bone loss. The survey was carried out in Taiji, Wakayama Prefecture, Japan. From a list of inhabitants aged 40–79 years, 400 participants (50 men and 50 women in each of four age groups) were selected randomly. Bone mineral density (BMD) was measured, and blood and urine samples of all participants were examined to obtain values for eight biochemical markers: alkaline phosphatase (ALP), bone Gla protein (BGP), type I procollagen (carboxyterminal peptide of type I procollagen; PICP), cross-linked carboxyterminal telopeptide region of type I collagen (ICTP), and urinary excretion of calcium (Ca), phosphate (P), pyridinoline (Pyr), and deoxypyridinoline (D-Pyr). Each marker was evaluated as a predictor of the rate of bone change in lumbar spine and femoral neck BMD over a 3-year period. The value of Pyr was significantly related to the change of lumbar spine BMD in men (P= 0.009), and that of BGP was found to be significant in women (P= 0.045). By contrast, none of the bone markers significantly correlated with bone loss at the femoral neck. The coefficient of determination at the lumbar spine was 5% and 7% at the femoral neck only. We conclude that biochemical markers of bone turnover cannot predict bone loss rates in middle-aged or elderly Japanese men and women over a 3-year period with sufficient accuracy for use in clinical decision making.
    Type of Medium: Electronic Resource
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  • 12
    Electronic Resource
    Electronic Resource
    Springer
    Archives of environmental contamination and toxicology 34 (1998), S. 152-157 
    ISSN: 1432-0703
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Abstract. Laboratory toxicity data contrasting responses of aquatic organisms to insecticides are important for focusing on sensitive species (steepest exposure-response slope) exposed to aqueous concentrations of these insecticides in field studies. These data also allow prediction of expected responses of aquatic species to a range of insecticide concentrations in situ. Aqueous 48-h toxicity tests were performed to contrast responses of Daphnia magna Straus, Hyalella azteca Saussure, Chironomus tentans Fabricius, and Pimephales promelas Rafinesque to acetylcholinesterase-inhibiting insecticides: chlorpyrifos, aldicarb, and chlordane. As expected, invertebrates tested (H. azteca, C. tentans, and D. magna) were ≥ 200 times more sensitive than the vertebrate P. promelas to chlorpyrifos exposures. H. azteca was approximately 3.5 times more sensitive to chlorpyrifos (453% mortality/μg/L) than D. magna (128% mortality/μg/L). For both aldicarb and chlordane, C. tentans was the most sensitive species tested (2.44 and 2.54% mortality/μg/L, respectively). Differences in chlordane potency for test species varied only by a factor of approximately 2–3 (0.88% mortality/μg/L for H. azteca to 2.54% mortality/μg/L for C. tentans). Although point estimates of population responses such as LC50s, NOECs, and LOECs are of some utility for predicting effects of pesticides in aquatic systems, exposure-response slopes are also useful for extrapolation of laboratory data to diverse field situations, especially where sediment sorption may regulate insecticide exposure or bioavailability.
    Type of Medium: Electronic Resource
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  • 13
    Electronic Resource
    Electronic Resource
    Springer
    Bulletin of environmental contamination and toxicology 55 (1995), S. 142-148 
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Type of Medium: Electronic Resource
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  • 14
    Electronic Resource
    Electronic Resource
    Springer
    Hydrobiologia 312 (1995), S. 191-208 
    ISSN: 1573-5117
    Keywords: index of biotic integrity ; stream ; fish ; erosion ; sediment ; physical habitat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Indices of biotic integrity (1131) were computed for two annual fish collections from 27 locations along the bluffline bordering the Mississippi River alluvial plain in northwestern Mississippi. Study sites exhibited varying degrees of physical habitat degradation due to accelerated channel erosion. Objectives of index application were to quantify existing environmental quality and to test the IBI as a tool for relating fish population characteristics to physical degradation. Physical habitat data were collected concurrently with fish at all sites, and physical habitat descriptors were compared with the IBI scores and component metrics. Three to 23 fish species were captured from each site, and species richness explained 64–70% of the variance in IBI scores. Fish collections were dominated by insectivores tolerant of habitat and water quality degradation. Suckers and piscivores were relatively uncommon. The IBI scores were generally not reflective of physical habitat conditions. Variation in IBI scores was indicative of only the grossest differences in physical habitat quality. Weak relationships between physical habitat quality and IBI scores may have been due to large temporal variations in biotic integrity typical of degraded habitats. Alternatively, water quality degradation, which we did not measure, may have confounded relationships between physical habitat and fish metrics. Regional application of the IBI as a habitat assessment tool in landscapes with widespread physical degradation must overcome lack of suitable reference sites, large temporal variation in IBI scores, and small numbers of fish per collection, leading to lower confidence levels for IBI scores. The scarcity of lightly impacted sites may hinder detection of biotic integrity response along gradients of physical habitat quality.
    Type of Medium: Electronic Resource
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  • 15
    Electronic Resource
    Electronic Resource
    Springer
    Journal of radioanalytical and nuclear chemistry 233 (1998), S. 257-264 
    ISSN: 1588-2780
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract A physics-based approach to gamma-ray response-function generation is presented in which the response of CdZnTe detectors is modeled from first principles. Numerical modeling is used to generate response functions needed for spectrum analysis for general detector configurations (e.g., electrode design, detector materials and geometry, and operating conditions). With numerical modeling, requirements for calibration and characterization are significantly reduced. Elements of the physics-based model, including gamma-ray transport, charge carrier drift and diffusion, and circuit response, are presented. Calculated and experimental gamma-ray spectra are compared for a coplanar-grid CdZnTe detector.
    Type of Medium: Electronic Resource
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  • 16
    ISSN: 1573-5117
    Keywords: stream restoration ; fish ; erosion ; sediment ; physical habitat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Channel incision has major impacts on stream corridor ecosystems, leading to reduced spatial habitat heterogeneity, greater temporal instability, less stream-floodplain interaction, and shifts in fish community structure. Most literature dealing with channel incision examines physical processes and erosion control. A study of incised warmwater stream rehabilitation was conducted to develop and demonstrate techniques that would be economically feasible for integration with more orthodox, extensively employed watershed stabilization techniques (e.g., structural bank protection, grade control structures, small reservoirs, and land treatment). One-km reaches of each of five northwest Mississippi streams with contributing drainage areas between 16 and 205 km2 were selected for a 5-year study. During the study two reaches were modified by adding woody vegetation and stone structure to rehabilitate habitats degraded by erosion and channelization. The other three reaches provided reference data, as two of them were degraded but not rehabilitated, and the third was only lightly degraded. Rehabilitation approaches were guided by conceptual models of incised channel evolution and fish community structure in small warmwater streams. These models indicated that rehabilitation efforts should focus on aggradational reaches in the downstream portions of incising watersheds, and that ecological status could be improved by inducing formation and maintenance of stable pool habitats. Fish and physical habitat attributes were sampled from each stream during the Spring and Fall for 5 years, and thalweg and cross-section surveys were performed twice during the same period. Rehabilitation increased pool habitat availability, and made the treated sites physically more similar to the lightly degraded reference site. Fish communities generally responded as suggested by the aforementioned conceptual model of fish community structure. Species composition shifted away from small colonists (principally cyprinids and small centrarchids) toward larger centrarchids, catostomids, and ictalurids. Fish density and species richness increased at one rehabilitated site but remained stable at the other, suggesting that the sites occupied different initial states and endpoints within the conceptual model, and differed in their accessibility to sources of colonizing organisms. These experiments suggest that major gains in stream ecosystem rehabilitation can be made through relatively modest but well-designed efforts to modify degraded physical habitats.
    Type of Medium: Electronic Resource
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  • 17
    Electronic Resource
    Electronic Resource
    Springer
    Minerva 5 (1967), S. 585-587 
    ISSN: 1573-1871
    Source: Springer Online Journal Archives 1860-2000
    Topics: Education , Nature of Science, Research, Systems of Higher Education, Museum Science
    Type of Medium: Electronic Resource
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  • 18
    Electronic Resource
    Electronic Resource
    Springer
    Discrete event dynamic systems 5 (1995), S. 115-140 
    ISSN: 1573-7594
    Keywords: time-parallel simulation ; asynchronous transfer mode networks ; burst-level simulation ; statistical multiplexer ; cellloss ratio ; broadband integrated services digital network
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract The simulation of high-speed telecommunication systems such as ATM (Asynchronous Transfer Mode) networks has generally required excessively long run times. This paper reviews alternative approaches using parallelism to speed up simulations of discrete event systems, and telecommunication networks in particular. Subsequently, a new simulation method is introduced for the fast parallel simulation of a common network element, namely, a work-conserving finite capacity statistical multiplexer of bursty ON/OFF sources arriving on input links of equal peak rate. The primary performance measure of interest is the cell loss ratio, due to buffer overflows. The proposed method is based on two principal techniques: (1) the derivation of low-level (cell level) statistics from a higher level (burst level) simulation and (2) parallel execution of the burst level simulation program. For the latter, atime-division parallel simulation method is used where simulations operating at different intervals of simulated time are executed concurrently on different processors. Both techniques contribute to the overall speedup. Furthermore, these techniques support simulations that are driven by traces of actual network traffic (trace-driven simulation), in addition to standard models for source traffic. An analysis of this technique is described, indicating that it offers excellent potential for delivering good performance. Measurements of an implementation running on a 32 processor KSR-2 multiprocessor demonstrate that, for certain model parameter settings, the simulator is able to simulate up to 10 billion cell arrivals per second of wallclock time.
    Type of Medium: Electronic Resource
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  • 19
    ISSN: 1434-6079
    Keywords: PACS. 34.70.+e Charge transfer - 36.40.-c Atomic and molecular clusters - 36.40.Qv Stability and fragmentation of clusters
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract: The destruction cross-section for 22.5 and 50 keV C1- , for 10 and 50 keV C8 1- and for 50 and 75 keV C60 1- clusters in collisions with H2 has been measured by an attenuation method. The destruction of the cluster anions is dominated by electron detachment rather than fragmentation and is of the order of the geometric cross-section. The cross-sections vary little with bombarding energy.
    Type of Medium: Electronic Resource
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  • 20
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: A major part of current effort in improving artificial hemodialysis techniques concerns the development of improved membrane structures. Although blood compatibility of membranes is a part of the Battelle program, this discussion is confined to membrane composition, structure, and transport. On the basis of a need for improved hemodialysis techniques, membranes for use in the artificial kidney were prepared and evaluated for urea, creatinine, and uric acid permeability. Water-soluble polymers were crosslinked to form insoluble, but swellable, membranes. Faster metabolic waste transfer than with the conventional cellulosic membranes was obtained with diisocyanate-crosslinked poly (vinyl pyrrolidone) and poly (vinyl pyrrolidone)-dextran membranes and with membranes obtained by crosslinking poly (vinyl alcohol) with polyfunctional aldehydes. Membranes prepared from emulsions of vinyl pyrrolidone-ethyl acrylate and vinyl pyrrolidone-styrene copolymers had exceptionally high urea and creatinine dialysis rates, but were deficient in uric acid transfer. This shortcoming was corrected by incorporating solutes such as sucrose into the membranes followed by leaching. Another important approach concerned the development of a relatively high-strength membrane based on an impermeable nylon resin. Permeability of these membranes which have dialysis characteristics superior to those currently used was obtained through the addition of DMSO and one of several other additives to the coating solution.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
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