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  • 1995-1999  (75)
  • 1985-1989  (50)
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Year
  • 11
    Electronic Resource
    Electronic Resource
    The archives of Société Générale: from a project to reality (1998)
    Cambridge : Cambridge University Press
    Financial history review 5 (1998), S. 87-98 
    Details
    ISSN: 0968-5650
    Source: Cambridge Journals Digital Archives
    Topics: History , Economics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1017/S0968565000001438
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  • 12
    Electronic Resource
    Electronic Resource
    Specific sodium dependence of a nitrate reductase in a marine bacterium (1987)
    Oxford, UK : Blackwell Publishing Ltd
    FEMS microbiology letters 48 (1987), S. 0 
    Details
    ISSN: 1574-6968
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Abstract The two key enzymes of denitrification, the nitrate and nitrate reductases, were studied in a marine organism, Pseudomonas nautica, strain 617. Both enzymes were grown under anaerobic conditions with either nitrate or nitrous oxide as electron acceptor. The effect of sodium on these enzymes was studied. Only sodium activated the membranous and purified nitrate reductase, and none of the salts affected nitrite reductase.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1574-6968.1987.tb02505.x
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  • 13
    Electronic Resource
    Electronic Resource
    Cloning and sequencing of the novel abortive infection gene abiH of Lactococcus lactis ssp. lactis biovar. diacetylactis S94 (1996)
    Oxford, UK : Blackwell Publishing Ltd
    FEMS microbiology letters 142 (1996), S. 0 
    Details
    ISSN: 1574-6968
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Abstract A gene which encodes resistance by abortive infection (Abi+) to bacteriophage was cloned from Lactococcus lactis ssp. lactis biovar. diacetylactis S94. This gene was found to confer a reduction in efficiency of plating and plaque size for prolate-headed bacteriophage φ53 (group I of homology) and total resistance to the small isometric-headed bacteriophage φ59 (group III of homology). The cloned gene is predicted to encode a polypeptide of 346 amino acid residues with a deduced molecular mass of 41 455 Da. No homology with any previously described genes was found. A probe was used to determine the presence of this gene in two strains on 31 tested.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1574-6968.1996.tb08446.x
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  • 14
    Electronic Resource
    Electronic Resource
    X-ray study of and structural approach to the incommensurate perovskite Pb2CoWO6 (1995)
    Copenhagen : International Union of Crystallography (IUCr)
    Acta crystallographica 51 (1995), S. 48-54 
    Details
    ISSN: 1600-5740
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0108768194011109
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  • 15
    Electronic Resource
    Electronic Resource
    Phase-transition-induced twinning in the 1:1 adduct of hexamethylenetetramine and azelaic acid (1999)
    Copenhagen : International Union of Crystallography (IUCr)
    Acta crystallographica 55 (1999), S. 448-458 
    Details
    ISSN: 1600-5740
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Notes: The title compound, C6H12N4\cdotC9H16O4, undergoes several thermotropic phase transitions. The crystalline structure is layered, with sheets of azelaic acid linked to sheets of hexamethylenetetramine by hydrogen bonds. In the room-temperature phase, the azelaic acid molecules are disordered. By lowering the temperature, this disorder partially disappears. The ordering is clearly observed in reciprocal space where on the rods of diffuse scattering, present in the room-temperature phase, a series of superstructure reflections emerges. This phase transition leads to twin-lattice quasi-symmetry (TLQS) twinning. The structure of this twinned phase is explored in this paper. There are two orientational domains linked by a mirror plane which relates disordered orientations of the acid molecules above the phase transition. A single domain has space group P2_1/c. The structure has been solved and refined on the complete set of data to R1 = 0.0469. The chains remain partially disordered, showing two acid groups with unequal population: the major form corresponding to a carboxylic acid and the minor to a carboxylate. The ordering of the structure, when going through the phase transition, is interpreted in terms of stabilization by C—H...O hydrogen bonding. A least-squares estimator of the twinning volume ratio is developed that gives an expression for the twinning ratio in terms of the intensities of nonoverlapping reflections. The twinning ratio obtained in the structure refinement compares very well with that obtained from this estimator.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0108768198017200
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  • 16
    Electronic Resource
    Electronic Resource
    Drug extrapyramidal side effects. CYP2D6 genotypes and phenotypes (1999)
    Springer
    European journal of clinical pharmacology 55 (1999), S. 659-665 
    Details
    ISSN: 1432-1041
    Keywords: Key words Extrapyramidal drug side effects ; CYP2D6 ; Genetic polymorphism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Abstract Objective: Among Caucasians, a lack of cytochrome P 450 enzyme CYP2D6 is observed in 5–10% of individuals, named poor metabolizers (PMs). A consequence may be an impaired metabolism of many drugs such as most of the psychotropic drugs with an increased risk of drug side effects. This enzyme is also involved in the metabolism of endogenous compounds, including neurotransmitters such as dopamine and dopamine-related neurotransmitters which play a role in the mechanism of action of extrapyramidal drug side effects. The present study investigates whether patients who have developed and those who have not developed extrapyramidal drug side effects differ in their CYP2D6 genotypes and phenotypes. Methods: The CP2D6 genotype (method involving restriction length fragment polymorphism and polymerase chain reaction-single strand conformation polymorphism) was determined in 65 drug-treated in-patients, and the CYP2D6 phenotype (with dextromethorphan probe) in 62 of them. Two groups were constituted, one with 22 patients who had developed extrapyramidal drug side effects, and the second with 43 patients without such side effects. Results: In the whole population, there was an over-representation of PM phenotypes – more marked in the first group than the second (45% vs 14%). Concerning the genotypes, we observed that the percentage of functional alleles (with extensive metabolic capacity) was higher in group 2, whereas the percentage of non-functional alleles (without metabolic activity) was higher in group 1; this frequency difference was only marginally significant (χ2 5.95; P 〈 0.0509; degrees of freedom=2). Consequently, there was a higher percentage of genotypes with no (extensive) functional alleles in the group of patients suffering from extrapyramidal side effects than in the other group (P 〈 0.00001). Conclusion: CYP2D6-impaired metabolic capacity may be a contributory factor in extrapyramidal drug side effects.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002280050689
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  • 17
    Electronic Resource
    Electronic Resource
    Comparative study of contaminants in the mudpuppy (amphibia) and the common snapping turtle (reptilia), St. Lawrence River, Canada (1995)
    Springer
    Archives of environmental contamination and toxicology 28 (1995), S. 184-194 
    Details
    ISSN: 1432-0703
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Abstract Levels of organochlorine pesticides, polychlorinated biphenyl (PCB) congeners and mercury were measured in mudpuppy bodies, livers and gonads and in snapping turtle eggs to determine how the composition and concentration of these bioaccumulated contaminants differ between the two species. Furthermore, the geographic variation in contamination patterns were examined between the highly polluted St. Lawrence River and the much less polluted Ottawa River, Canada. Principal component analysis performed with 69 tissue samples (30 samples of mudpuppy tissues and 39 turtle egg clutches) indicated distinct contamination patterns in the two species for PCB congeners; PCB congener composition in mudpuppies resembled the pattern reported for fish while the turtle pattern was more akin to the bird pattern. This could be related to the metabolic capacity of each species. The organochlorine pesticide contamination profile was also species-specific although highly variable among locations. Contamination profiles were similar for mudpuppy gonads and carcasses but lipidweight basis concentrations were often a little higher in gonads. In both species, geographic variations in contamination patterns were noticeable and significant differences in contamination levels were detected between Ottawa River and St. Lawrence River samples. However, in both species, concentrations varied considerably within a single location. Sources of variability are discussed although the basic life history of these species in the St. Lawrence River system is relatively unknown.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00217615
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  • 18
    Electronic Resource
    Electronic Resource
    The design and use of aerated microcosms inmineralization studies (1999)
    Springer
    Biodegradation 10 (1999), S. 437-442 
    Details
    ISSN: 1572-9729
    Keywords: Aeration ; bioremediation ; composting ; glucose ; hexadecane ; microcosm
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Energy, Environment Protection, Nuclear Power Engineering , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract The need for aeration of microcosms duringmineralization of 14C-labeled compounds in highoxygen demand environments was assessed using activecompost-soil mixtures as the model system. Rapidmineralization of 14C-hexadecane occurred incontinuously aerated microcosms while nomineralization occurred in unaerated microcosms. Dailyflushing with air also yielded no mineralization.Mineralization of 14C-glucose was much lessdependent on aeration. The alkaline solution volumeand number of CO2 traps required for continuousaeration were calculated and tested experimentally.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1008316727321
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  • 19
    Electronic Resource
    Electronic Resource
    Hydrocarbon influence on denitrification in bioturbated Mediterranean coastal sediments (1997)
    Springer
    Hydrobiologia 345 (1997), S. 67-77 
    Details
    ISSN: 1573-5117
    Keywords: bioturbation ; denitrification ; hydrocarbons ; macrofauna ; organic matter ; in situ experiment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract An in situ experiment has been carried out inbioturbated Mediterranean coastal marine sediments (Gulfof Fos) in order to study the influence of hydrocarbons ondenitrification after 1, 4 and 6 months. In theabsence of hydrocarbons in the control sediments, the presenceof macrofauna stimulated denitrificationby 160%. This stimulation is induced by sediment reworkingthat favours both direct NO-3 supply fromthe water column and the penetration of O{2}, which in turnstimulated nitrification, the other source ofNO-3 in sediment. The presence of hydrocarbons in theexperimental sediments either stimulated orinhibited the denitrification. The denitrification response tothe presence of hydrocarbon is dependent onthe quantity of matter buried by the macrofauna activity. Insmall quantities, the organic matter relatedto hydrocarbons 120% enhanced the denitrification compared tothe controls. On the other hand, whenburied hydrocarbon concentrations were higher (〉100 mgsaturated hydrocarbon fraction kg-1 drysediment), the denitrification was inhibited.On the basis of the results obtained, a descriptive model ofthe patterns of denitrification in relation to the presence ofmacrofauna and the distribution ofhydrocarbons in sediments is proposed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1002931432250
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  • 20
    Electronic Resource
    Electronic Resource
    Simultaneous occurrence of denitrification and nitrate ammonification in sediments of the French Mediterranean Coast (1998)
    Springer
    Hydrobiologia 389 (1998), S. 169-182 
    Details
    ISSN: 1573-5117
    Keywords: nitrate ammonification ; denitrification ; 15N ; acetylene ; marine sediment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Dissimilatory nitrate reductions in coastal marine sediment of Carteau Cove (French Mediterranean Coast) were studied between April 1993 and July 1994. Simultaneous determination of denitrification and dissimilatory nitrate reduction to ammonium was achieved by using a combination of acetylene blockage and 15N techniques. After short incubations (maximum 5 h), a part of 15N labelled nitrate added to the sediment was recovered as ammonium without incorporation in organic matter. The result indicate that a fraction of nitrate was reduced to ammonium by a dissimilatory mechanism instead of denitrifying. Denitrifying and nitrate ammonifying activities ranged from 0 to 19.8 μmol l-1 d-1 and from 2.3 to 83.2 μmol l-1 d-1, respectively. Denitrification rates were highest in early spring whereas nitrate ammonification were highest in fall. The recovery of nitrate reduced as N2O-N plus ammonium was between 40 and 100%, the highest nitrogen losses were recorded in July. Depending on the station and time of year denitrification accounted for between 0 and 43% of the total nitrate reduction whereas dissimilatory nitrate reduction to ammonium (DNRA) accounted for between 18 and 100%. The reduction rate data suggest that the pathway of nitrate reduction to ammonium may be important in coastal sediments.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1003585115481
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