ISSN:
1420-9071
Schlagwort(e):
Adrenaline
;
epinephrine
;
phenylethanolamine-N-methyltransferase
;
PNMT
;
epinine
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Biologie
,
Medizin
Notizen:
Summary Adrenaline (A) is synthesized in the adrenal medullae by the enzyme phenylethanolamine-N-methyltransferase (PNMT). After surgical removal of the adrenal medullae tissue A levels ranged from 22% of control in the heart to 125% of control in the liver. Use of a novel assay to measure tissue A formation revealed that many tissues can synthesize A using PNMT and another enzyme that N-methylates both noradrenaline and dopamine. These enzymes are non-neuronal, inducible and synthesize a major fraction of tissue and urine A.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF01974566
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