ISSN:
1434-193X
Schlagwort(e):
Heterocycles
;
Alkaloids
;
Castanospermine
;
Metathesis
;
Azasugars
;
Manzamine A
;
Chemistry
;
General Chemistry
Quelle:
Wiley InterScience Backfile Collection 1832-2000
Thema:
Chemie und Pharmazie
Notizen:
-The application of the ring-closing metathesis (RCM) reaction to the construction of a wide variety of nitrogen-containing ring systems is described. The examples include pyrrolizidine, indolizidine, and quinolizidine derivatives related to azasugars. A formal total synthesis of castanospermine (5) is presented. The utilisation of two RCM steps in the synthetic sequence leading to the multicyclic ABCDE nucleus 7 of the complex alkaloid manzamine A (6) is discussed.
Zusätzliches Material:
3 Ill.
Materialart:
Digitale Medien
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