ISSN:
1573-4927
Schlagwort(e):
rats
;
Es-4
;
linear order
;
clusters
;
linkage group V (LGV)
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Biologie
,
Chemie und Pharmazie
Notizen:
Abstract There are three different linear orders of esterase loci of linkage group V (LGV) in the rat (Rattus norvegicus). The first isEs-2-Es-3-Es-1, the secondEs-3-(Es-2,Es-4)-Es-1, and the thirdEs-3-Es-2-Es-1-Es-4. We carried out mating experiments to define the order clearly. Linkage analyses of the four esterase loci,Es-1, Es-2, Es-3, andEs-4, were carried out using two inbred strains carrying different alleles at the four loci. Six locus combinations examined in this study were as follows:Es-1-Es-2, Es-1-Es-3, Es-1-Es-4, Es-2-Es-3, Es-2-Es-4, and Es-3-Es-4. The recombination frequencies of each combination were 6.3, 6.3, 6.3, 5.2, 1.8, and 3.4%, respectively. The first recombination betweenEs-2 andEs-4 was observed. We propose that the esterase loci of LGV be classified into three clusters according to distances between the loci. The linear order of the four loci is shown to be as follows: [Es-3] (cluster II)—3.4±2.4%—[Es-4—1.8±1.7%—Es-2] (cluster III)—6.3±6.1%—[Es-1] (cluster I).
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF02396056
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