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  • 1
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    In:  Nature, Amsterdam, Elsevier Scientific Publishing Company, vol. 436, no. 7050, pp. 499-503, pp. 1390
    Publication Date: 2005
    Keywords: Geothermics ; particle ; physics ; beta ; decay
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  • 2
    Publication Date: 2018-06-05
    Description: The U-slot rectangular patch antenna (Figure I) has been found experimentally to provide impedance and gain bandwidths of about 300 without the need of stacked or coplanar parasitic elements [1,2]. In this paper, simulation results of the U-slot patch using FDTD analysis are presented. Comparison with measured results are given.
    Keywords: Electronics and Electrical Engineering
    Type: IEEE Antennas and Propagation Society International Symposium 1997. Volume 4: Digest; 2111-2114; IEEE-Catalog-97CH36122-Vol-4
    Format: text
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  • 3
    Publication Date: 2019-07-13
    Description: The fundamental problem in the evolution of matter is to understand how structure-function relationships are formed and increase in complexity from the molecular level all the way to a genetic system. We have created a system where structure-function relationships arise naturally and without the need of ad hoc function assignments to given structures. The idea was inspired by neural networks, where the structure of the net embodies specific computational properties. In this system networks interact with other networks to create connections between the inputs of one net and the outputs of another. The newly created net then recomputes its own synaptic weights, based on anti-hebbian rules. As a result some connections may be cut, and multiple nets can emerge as products of a 'reaction'. The idea is to study emergent reaction behaviors, based on simple rules that constitute a pseudophysics of the system. These simple rules are parameterized to produce behaviors that emulate chemical reactions. We find that these simple rules show a gradual increase in the size and complexity of molecules. We have been building a virtual artificial chemistry laboratory for discovering interesting reactions and for testing further ideas on the evolution of primitive molecules. Some of these ideas include the potential effect of membranes and selective diffusion according to molecular size.
    Keywords: Cybernetics, Artificial Intelligence and Robotics
    Type: ANNIE 2002; Nov 10, 2002 - Nov 13, 2002; Saint Louis, MO; United States
    Format: text
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  • 4
    Publication Date: 2019-07-13
    Description: Unsteady three-dimensional RANS simulations have been performed on a highly loaded transonic turbine stage and results are compared to steady calculations as well as experiment. A low Reynolds number k- turbulence model is employed to provide closure for the RANS system. A phase-lag boundary condition is used in the periodic direction. This allows the unsteady simulation to be performed by using only one blade from each of the two rows. The objective of this paper is to study the effect of unsteadiness on rotor heat transfer and to glean any insight into unsteady flow physics. The role of the stator wake passing on the pressure distribution at the leading edge is also studied. The simulated heat transfer and pressure results agreed favorably with experiment. The time-averaged heat transfer predicted by the unsteady simulation is higher than the heat transfer predicted by the steady simulation everywhere except at the leading edge. The shock structure formed due to stator-rotor interaction was analyzed. Heat transfer and pressure at the hub and casing were also studied. Thermal segregation was observed that leads to the heat transfer patterns predicted by steady and unsteady simulations to be different.
    Keywords: Aerodynamics
    Type: NASA/TM-2010-216064 , GT2009-60322 , E-17109 , Turbo Expo 2009; Jun 08, 2009 - Jun 12, 2009; Orlando, FL; United States
    Format: application/pdf
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  • 5
    Publication Date: 2017-07-18
    Description: To survey hepatitis B virus (HBV) integration in liver cancer genomes, we conducted massively parallel sequencing of 81 HBV-positive and 7 HBV-negative hepatocellular carcinomas (HCCs) and adjacent normal tissues. We found that HBV integration is observed more frequently in the tumors (86.4%) than in adjacent liver tissues (30.7%). Copy-number variations (CNVs) were significantly increased at HBV breakpoint locations where chromosomal instability was likely induced. Approximately 40% of HBV breakpoints within the HBV genome were located within a 1,800-bp region where the viral enhancer, X gene and core gene are located. We also identified recurrent HBV integration events (in ≥4 HCCs) that were validated by RNA sequencing (RNA-seq) and Sanger sequencing at the known and putative cancer-related TERT, MLL4 and CCNE1 genes, which showed upregulated gene expression in tumor versus normal tissue. We also report evidence that suggests that the number of HBV integrations is associated with patient survival.
    Type: Article , PeerReviewed
    Format: text
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