ISSN:
0570-0833
Keywords:
Corrinoids
;
Chemistry
;
General Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Work towards a synthesis of vitamin B12 has inspired a new type of corrin synthesis. The key step is a light-induced 1,16-hydrogen transfer leading to an antarafacial (π→σ)-cycloisomerization of a seco-corrinoid metal complex. The construction of the seco-corrinoid ligand system is achieved by coupling monocyclic ring precursors in their enamide or enamine form through the methods of sulfide-contraction via oxidative coupling and of iminoester-enamine condensation.
Additional Material:
1 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/anie.196903431
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