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  • Articles  (138)
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  • 1
    Electronic Resource
    Electronic Resource
    Shear field mapping in actin networks by using magnetic tweezers (1996)
    Springer
    European biophysics journal 24 (1996), S. 348-353 
    Details
    ISSN: 1432-1017
    Keywords: Biogels ; actin networks ; magnetic tweezers ; microrheology of polymer networks ; cytoskeleton viscoelasticity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Abstract An improved magnetic bead microrheometer based on phase contrast microscopy allowing high resolution measurements of local deformations within macromolecular networks is applied to study local viscoelastic properties of cross-linked actin networks. By embedding non-magnetic colloidal beads as probes into the networks, the spatial variation of the strain field within cross-linked actin networks can be mapped. Moreover, the Poisson ratio and shear modulus can be measured locally.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00180376
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  • 2
    Electronic Resource
    Electronic Resource
    Obituary for John E. Hunter (2002)
    Oxford, UK and Boston, USA : Blackwell Publishers Ltd
    International journal of selection and assessment 10 (2002), S. 0 
    Details
    ISSN: 1468-2389
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Economics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/1468-2389.00207
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  • 3
    Electronic Resource
    Electronic Resource
    Fixed Effects vs. Random Effects Meta-Analysis Models: Implications for Cumulative Research Knowledge (2000)
    Oxford, UK and Boston, USA : Blackwell Publishers Ltd
    International journal of selection and assessment 8 (2000), S. 0 
    Details
    ISSN: 1468-2389
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Economics
    Notes: Research conclusions in the social sciences are increasingly based on meta-analysis, making questions of the accuracy of meta-analysis critical to the integrity of the base of cumulative knowledge. Both fixed effects (FE) and random effects (RE) meta-analysis models have been used widely in published meta-analyses. This article shows that FE models typically manifest a substantial Type I bias in significance tests for mean effect sizes and for moderator variables (interactions), while RE models do not. Likewise, FE models, but not RE models, yield confidence intervals for mean effect sizes that are narrower than their nominal width, thereby overstating the degree of precision in meta-analysis findings. This article demonstrates analytically that these biases in FE procedures are large enough to create serious distortions in conclusions about cumulative knowledge in the research literature. We therefore recommend that RE methods routinely be employed in meta-analysis in preference to FE methods.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/1468-2389.00156
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  • 4
    Electronic Resource
    Electronic Resource
    Crystallization and preliminary X-ray crystallographic analysis of PdxJ, the pyridoxine 5′-phosphate synthesizing enzyme (2000)
    Copenhagen : International Union of Crystallography (IUCr)
    Acta crystallographica 56 (2000), S. 1045-1048 
    Details
    ISSN: 1399-0047
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Notes: The enzyme PdxJ catalyzes the condensation of 1-deoxy-D-xylulose-5-phosphate (DXP) and 1-amino-3-oxo-4-(phosphohydroxy)propan-2-one to form pyridoxine 5′-phosphate (PNP). The protein from Escherichia coli has been crystallized in several forms under different conditions. The best diffracting crystals were obtained by a combination of the hanging-drop vapour-diffusion and microseeding techniques. Using an in-house image plate, the PdxJ crystals diffracted under cryo-conditions to 2.6 Å resolution. The space group has been determined as C2221, with unit-cell parameters a = 132.5, b = 154.4, c = 131.4 Å, corresponding to four monomers per asymmetric unit. In the search for heavy-atom derivatives, a mercury derivative has been interpreted. The 12 mercury sites located are related by 222 symmetry and, in combination with self-rotation search analyses and gel-filtration experiments, indicate the quaternary assembly of PdxJ into octamers with 422 symmetry.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0907444900007368
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  • 5
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    RESEARCH NOTES AND COMMUNICATIONS (1975)
    Chicago : Periodicals Archive Online (PAO)
    Journal of marketing research. 12:3 (1975:Aug.) 347 
    Details
    ISSN: 0022-2437
    Topics: Economics
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:b178-1975-012-03-000012
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  • 6
    Electronic Resource
    Electronic Resource
    On Normal Mode Aided Modelling: Application to Asian Monsoon (2000)
    Springer
    Meteorology and atmospheric physics 73 (2000), S. 189-210 
    Details
    ISSN: 1436-5065
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geography , Physics
    Notes: Summary A new concept of utilizing generalized normal mode initialization (NMI) for modelling is investigated. This NMI-balancing adapts real data to model solutions. For eigenmodes of typical (climatological) structure and a simple 1- or more-layer shallow water model, anomalous flow of special episodes or events can be identified with mode groups giving distinctive signals. If these signals are part of the model solution or of the complement of the data to the model solution and how this is changed by introducing additional physical mechanisms to the model, gives hints for improvement. In applying this to multi-scale interactions of Asian monsoon, in particular a seventeen-years background knowledge and the anomalous flow of years 1991, 1977, 1978 we have a challenging test frame. Particular topics are: (1) Mei Yu rains in China, the representation of particular aspects of them by certain mode groups, the degree of independence of the corresponding signals on other modes, and the role of dissipation; (2) detection of El Niño-Southern Oscillation (ENSO) in atmospheric (reanalysis) data minus the NMI-balanced model solution; (3) Madden-Julian Oscillations (MJO) and the introduction of diabatic processes, and finally (4) aspects of dynamic stability. From among the results which are new or we simply have become aware of we pull out that atmospheric processes generally can be represented by modes or mode groups neither straight forward nor uniquely. Introduction of some dissipation schemes to the model was not helpful but rather destroyed the realistic structure of atmospheric dynamics. A parameterization of diabatic processes passes signals present in the data but not in the NMI-balanced model solution through to such being part of the latter, in case of MJO but not yet in case of ENSO. Ocean dynamics proves to be indispensable. Nevertheless there are imprints of essential atmospheric processes hidden on certain (e.g., most unstable) modes and partially recovered by NMI-balancing.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s007030050073
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  • 7
    Electronic Resource
    Electronic Resource
    Card shuffling and a transformation on S n (1992)
    Springer
    Aequationes mathematicae 44 (1992), S. 11-34 
    Details
    ISSN: 1420-8903
    Keywords: 05A05
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Summary We consider two card shuffling schemes. The first, which has appeared in the literature previously ([G], [RB], [T]), is as follows: start with a deck ofn cards, and pick a random tuplet ∈ { 1, 2, ⋯, n} n ; interchange cards 1 andt 1, then interchange cards 2 andt 2, etc. The second scheme, which can be viewed as a transformation on the symmetric groupS n , is given by the restriction of the former shuffling scheme to tuplest which form a permutation of {1, 2,⋯,n}. We determine the bias of each of these shuffling schemes with respect to the sets of transpositions and derangements, and the expected number of fixed points of a permutation generated by each of these shuffling schemes. For the latter scheme we prove combinatorially that the permutation which arises with the highest probability is the identity. The same question is open for the former scheme. We refute a candidate answer suggested by numerical evidence [RB].
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01834201
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  • 8
    Electronic Resource
    Electronic Resource
    RNA interference detected 20 years ago? (2004)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 22 (2004), S. 267-268 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] To the editor: As your review in the December issue attests (Nat. Biotechnol. 21, 1457–1466, 2003), RNA interference has recently emerged as one of the hottest new research topics in science, an important research tool and potentially a new type of experimental therapy. I would like to bring ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0304-267b
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  • 9
    Electronic Resource
    Electronic Resource
    Viral influences on aflatoxin formation by Aspergillus flavus (1986)
    Springer
    Applied microbiology and biotechnology 24 (1986), S. 248-252 
    Details
    ISSN: 1432-0614
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Summary A nontoxigenic isolate of Aspergillus flavus (NRRL 5565) contains a viral genome consisting of 3 double-stranded RNA (ds-RNA) components with molecular weights of approximately 3 kb each. It thus shares a characteristical feature with a virus occuring in strains of Penicillium chrysogenum. Application of known inhibitors of doublestranded RNA virus synthesis results in stable aflatoxin formation by this originally nontoxigenic strain and the simultaneous loss of its ds-RNA traits. Since the inhibitor induced toxicity can be completely reverted by incubation with a virus from Penicillium chrysogenum (PcV), it is presumed that PcV or a functional related virus possibly constitutes the aflatoxin repressing determinant in Aspergillus flavus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00261546
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  • 10
    Electronic Resource
    Electronic Resource
    Electrophysiological and chemical analysis of sex pheromone communication system of the mottled umber,Erannis defoliaria (Lepidoptera: Geometridae) (1990)
    Springer
    Journal of chemical ecology 16 (1990), S. 1887-1897 
    Details
    ISSN: 1573-1561
    Keywords: Erannis defoliaria (Z,Z,Z)-3,6,9-nonadecatriene ; (Z,Z)-3,9-cis-6,7-epoxy-nonadecadiene ; sex pheromone ; identification ; electroantennogram ; single sensillum ; peripheral inhibitor ; Agriopis marginaria ; Colotois pennaria ; Lepidoptera ; Geometridae
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract (Z,Z,Z)-3,6,9-nonadecatriene (Z3,Z6,Z9–19Hy) and (Z,Z)-3,9-cis-6,7-epoxy-nonadecadiene (Z3,Z9-cis-6,7-epo-19Hy) were identified in pheromone gland extracts from femaleErannis defoliaria. The two components were found in a 1∶3 ratio, with the main component,Z3,Z9-cis-6,7-epo-19Hy present at an amount of about 1.5 ng per female. The components were identified by means of gas chromatography-mass spectrometry, gas chromatography-electroantennography and gas chromatography-single sensillum recordings. Single sensillum measurements on the male antenna showed two physiological types of sensilla. One type was characterized by a large spike amplitude cell responding toZ3,Z9-cis-6,7-epoxy-19Hy and a small spike amplitude cell responding toZ3,Z6,Z9–19Hy. A second type responded only with a large spike amplitude cell to the epoxide, and this cell was inhibited by the triene. Of the two pheromone components, the epoxide gave the higher response in the EAG tests. Preliminary field tests support the identification of the pheromone components. The epoxide was also found to be present in the extract of the pheromone gland ofColotois pennaria, and males ofC. pennaria andAgriopis marginaria were trapped by the mixture of the identified compounds.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01020502
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