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  • Articles  (52)
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  • 1
    Publication Date: 2018-03-29
    Description: Balancer chromosomes are multiply inverted and rearranged chromosomes used in Drosophila melanogaster for many tasks, such as maintaining mutant alleles in stock and complex stock construction. Balancers were created before molecular characterization of their breakpoints was possible, so the precise locations of many of these breakpoints are unknown. Here, we report or confirm the positions of the 14 euchromatic breakpoints on the 2 nd chromosome balancers SM1 , SM5 , CyO , and SM6a . This total includes three breakpoints involved in a complex rearrangement on SM5 that is associated with the duplication of two genomic regions. Unbiased sequencing of several balancers allowed us to identify stocks with incorrectly identified balancers as well as single and double crossover events that had occurred between 2 nd chromosome balancers and their homologs. The confirmed crossover events that we recovered were at least 2 Mb from the closest inversion breakpoint, consistent with observations from other balancer chromosomes. Balancer chromosomes differ from one another both by large tracts of sequence diversity generated by recombination and by small differences, such as single nucleotide polymorphisms (SNPs). Therefore, we also report loss-of-function mutations carried by these chromosomes and unique SNP and InDel polymorphisms present on only single balancers. These findings provide valuable information about the structure of commonly used 2 nd chromosome balancers and extend recent work examining the structure of X and 3 rd chromosome balancers. Finally, these observations provide new insights into how the sequences of individual balancers have diverged over time.
    Electronic ISSN: 2160-1836
    Topics: Biology
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  • 2
    Publication Date: 1970-01-01
    Print ISSN: 0149-1423
    Electronic ISSN: 1943-2674
    Topics: Geosciences
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 91 (1961), S. 0 
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 168 (1951), S. 163-164 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] In a seismic study of the crustal layers in the western Transvaal2, it was found that between 220 and 300 km. there was a large and well-defined phase which was rather more than 1 second early with respect to the Pt line (V-^ = 6-09 km./sec). It was pointed out that the early onsets could be ...
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 221 (1969), S. 930-933 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Body wave travel times and surface wave dispersion tend to favour the hypothesis that the low velocity layers are relatively thin zones of high velocity ...
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Geophysical journal international 6 (1953), S. 0 
    ISSN: 1365-246X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geosciences
    Notes: In an earlier paper it was suggested that it was failure in the region between 250 and 600 km below the surface which determined the periodicity of orogenic phenomena. In this paper estimates of the cross-sectional areas of the oceanic troughs and of the mass deficiencies reflected in the strips of large negative gravity anomalies are given and it is inferred that the interval between successive periods of failure is 50 million years.It is pointed out that if the troughs are formed in the manner described in the earlier paper then a regression of sea-level of about 70 metres will occur as a result of their formation. Finally some aspects of the development of the trough regions into mountain ranges are discussed qualitatively.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Geophysical journal international 4 (1937), S. 0 
    ISSN: 1365-246X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geosciences
    Notes: The paper discusses the effect of a weak layer in the upper mantle on the deformation of the crust arising from atmospheric loading, and on the isostatic compensation process. It also points out that S phases with periods of I second are much more strongly damped than S phases with periods of 10 seconds or more, and than P phases with short periods. The damping arising from a liquid layer is proportional to the square root of the frequency and does not provide a satisfactory explanation. Scattering of the kind suggested by Jeffreys, or any other mechanism leading to the firmoviscous law, gives rise to damping proportional to the square of the frequency and is sufficiently frequency sensitive to be consistent with the observations. The differences between P and S can only be accounted for in terms of different behaviour of the elastic constants for dilatational and distortional movements.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Geophysical journal international 3 (1936), S. 0 
    ISSN: 1365-246X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geosciences
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  • 9
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Geophysical journal international 105 (1991), S. 0 
    ISSN: 1365-246X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geosciences
    Notes: Analysis of the Early Rise traveltimes in the United States shows that on several of the profiles there are features which can be interpreted as indicating a low-velocity zone above 200 km, i.e. that the continental lithosphere thickness is less than 200 km. The explosion data from the Nevada Test Site, GNOME and Early Rise are all consistent with Lehmann's suggestion that there is a discontinuity at a depth of about 200 km. Comparison of the observed data between 15° and 23° with model calculations shows that the major differences between the western and central-eastern United States upper mantles occur above 200 km. It appears that the only reasonable explanation for the 200 km discontinuity is that it represents the termination of a zone of partial melting.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Geophysical journal international 7 (1956), S. 0 
    ISSN: 1365-246X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geosciences
    Notes: iA detailed study has been made of the remanent magnetization of five Pilansberg dykes, by means of measurements on oriented specimens of the rocks. Outcrops of the dykes prove to have suffered magnetic disturbance of their original thermo-remanent magnetization. Specimens from depths of a few thousand feet, taken in Witwatersrand gold mines, show highly consistent magnetisation of the basic parts of the dykes over considerable distances between sampling sites. The mean directions given by the five dykes agree well, and the mean direction from the five dykes gives a North-seeking magnetic pole with inclination +69.3 and azimuth N 24° E. Assuming thermo-remanent magnetisation by a geocentric dipole field, this places a North magnetic pole in latitude 71/2° N, longitude 421/ E at the time of intrusion of the dykes. The age of the dykes is uncertain, but is probably about 300 to 400 million years. Some of the specimens have been subjected to alternating magnetic fields in order to test the stability of their magnetisations. The basic specimens are found to be highly stable, being only slightly affected by fields of 100 to 300 oersteds. The possible implications of the results are discussed, in terms of hypotheses of polar wandering and continental drift.
    Type of Medium: Electronic Resource
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