ISSN:
1573-4978
Keywords:
HSV-1 infected cells
;
monensin
;
protein excretion
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Abstract HEp-2 cells, which were infected with HSV-1, excrete besides other proteins a soluble glycoprotein (Mr 125000–130000) related to the virus protein gC. The excretion of the glycoprotein and the production of extracellular virus particles is reduced to a similar extent when the cells were treated with monensin. Possible consequences of the excretion of soluble viral proteins to a modulation of the immune response are discussed.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00805636
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