ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • Articles  (67)
Collection
  • 1
    Publication Date: 2017-11-30
    Description: In this paper, the curing kinetics of 4,4′-Methylenebis epoxy resin(TGDDM) and m-Xylylenediamine(m-XDA) was investigated by non-isothermal differential scanning calorimetry(DSC) at various heating rates. Selected non-isothermal methods for analyzing curing kinetics were compared. The activation energy(E) and the correlation coefficient(R) were obtained by different isoconversional methods. The reaction order(n) was obtained by the activation energy in different isoconversional methods for the by Crane equation. The results show that the apparent activation energy are 65.23kJ/mol, 52.20 kJ/mol and 66.10 kJ/mol by using the method of Kissinger, Friedman and F-W-O, the reaction order are 0.911, 0.729 and 0.923 by using the method of Kissinger, Friedman and F-W-O.
    Print ISSN: 1757-8981
    Electronic ISSN: 1757-899X
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 2
    Publication Date: 2011-05-20
    Description: In this work, hexagonal solid solutions of (Gd 0.95 Eu 0.05 )(OH) 3 with two distinctive morphologies of nanorods and nanotubes were successfully synthesized via hydrothermal treatment of mixed nitrate solutions in the presence of ammonium hydroxide. The hydroxide samples exhibited characteristic Eu 3+ photoluminescence through the energy transfer from Gd 3+ to Eu 3+ and the self-excitation of Eu 3+ . The hydroxide precursors transformed into cubic (Gd 0.95 Eu 0.05 ) 2 O 3 at ~500 °C via an intermediate monoclinic (Gd 0.95 Eu 0.05 )OOH phase, and the Eu 3+ coordination accordingly experienced symmetry changes from D 3 h to C 2 v , and then to C 2 / S 6 . The cubic (Gd 0.95 Eu 0.05 ) 2 O 3 well retained the original morphologies of their p...
    Print ISSN: 1757-8981
    Electronic ISSN: 1757-899X
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 3
    Publication Date: 2009-03-28
    Description: The spread of HIV between immune cells is greatly enhanced by cell-cell adhesions called virological synapses, although the underlying mechanisms have been unclear. With use of an infectious, fluorescent clone of HIV, we tracked the movement of Gag in live CD4 T cells and captured the direct translocation of HIV across the virological synapse. Quantitative, high-speed three-dimensional (3D) video microscopy revealed the rapid formation of micrometer-sized "buttons" containing oligomerized viral Gag protein. Electron microscopy showed that these buttons were packed with budding viral crescents. Viral transfer events were observed to form virus-laden internal compartments within target cells. Continuous time-lapse monitoring showed preferential infection through synapses. Thus, HIV dissemination may be enhanced by virological synapse-mediated cell adhesion coupled to viral endocytosis.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756521/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756521/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hubner, Wolfgang -- McNerney, Gregory P -- Chen, Ping -- Dale, Benjamin M -- Gordon, Ronald E -- Chuang, Frank Y S -- Li, Xiao-Dong -- Asmuth, David M -- Huser, Thomas -- Chen, Benjamin K -- 5R24 CA095823-04/CA/NCI NIH HHS/ -- AI074420-02/AI/NIAID NIH HHS/ -- DP1 DA028866/DA/NIDA NIH HHS/ -- R01 AI074420/AI/NIAID NIH HHS/ -- R01 AI074420-01A2/AI/NIAID NIH HHS/ -- R01 AI074420-02/AI/NIAID NIH HHS/ -- S10RR09145-01/RR/NCRR NIH HHS/ -- ULRR024146/PHS HHS/ -- New York, N.Y. -- Science. 2009 Mar 27;323(5922):1743-7. doi: 10.1126/science.1167525.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Division of Infectious Diseases, Department of Medicine, Immunology Institute, Mount Sinai School of Medicine, New York, NY 10029, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19325119" target="_blank"〉PubMed〈/a〉
    Keywords: CD4-Positive T-Lymphocytes/*physiology/ultrastructure/*virology ; *Cell Adhesion ; Coculture Techniques ; Cytochalasin D/pharmacology ; Endocytosis ; HIV/*physiology/ultrastructure ; Humans ; Imaging, Three-Dimensional ; Jurkat Cells ; Microscopy, Confocal ; Microscopy, Electron, Transmission ; Microscopy, Video ; Receptors, CCR5/metabolism ; Receptors, CXCR4/metabolism ; Recombinant Fusion Proteins/metabolism ; *Virus Internalization ; gag Gene Products, Human Immunodeficiency Virus/*metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 4
    Publication Date: 2013-08-31
    Description: Invasion of microbial DNA into the cytoplasm of animal cells triggers a cascade of host immune reactions that help clear the infection; however, self DNA in the cytoplasm can cause autoimmune diseases. Biochemical approaches led to the identification of cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) synthase (cGAS) as a cytosolic DNA sensor that triggers innate immune responses. Here, we show that cells from cGAS-deficient (cGas(-/-)) mice, including fibroblasts, macrophages, and dendritic cells, failed to produce type I interferons and other cytokines in response to DNA transfection or DNA virus infection. cGas(-/-) mice were more susceptible to lethal infection with herpes simplex virus 1 (HSV1) than wild-type mice. We also show that cGAMP is an adjuvant that boosts antigen-specific T cell activation and antibody production in mice.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863637/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863637/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Li, Xiao-Dong -- Wu, Jiaxi -- Gao, Daxing -- Wang, Hua -- Sun, Lijun -- Chen, Zhijian J -- 5T32AI070116/AI/NIAID NIH HHS/ -- AI-093967/AI/NIAID NIH HHS/ -- R01 AI093967/AI/NIAID NIH HHS/ -- Howard Hughes Medical Institute/ -- New York, N.Y. -- Science. 2013 Sep 20;341(6152):1390-4. doi: 10.1126/science.1244040. Epub 2013 Aug 29.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9148, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23989956" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Antibodies, Viral/biosynthesis ; DNA, Viral/genetics/immunology ; Dendritic Cells/immunology ; Fibroblasts/immunology ; Herpes Simplex/*immunology ; *Herpesvirus 1, Human ; Interferon Regulatory Factor-3/genetics ; Interferon-beta/*biosynthesis/genetics ; Lymphocyte Activation ; Macrophages/immunology ; Mice ; Mice, Knockout ; Nucleotidyltransferases/genetics/*immunology ; Signal Transduction ; T-Lymphocytes/immunology ; Transfection
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 5
    Publication Date: 2014-12-20
    Description: Multivalent molecules with repetitive structures including bacterial capsular polysaccharides and viral capsids elicit antibody responses through B cell receptor (BCR) crosslinking in the absence of T cell help. We report that immunization with these T cell-independent type 2 (TI-2) antigens causes up-regulation of endogenous retrovirus (ERV) RNAs in antigen-specific mouse B cells. These RNAs are detected via a mitochondrial antiviral signaling protein (MAVS)-dependent RNA sensing pathway or reverse-transcribed and detected via the cGAS-cGAMP-STING pathway, triggering a second, sustained wave of signaling that promotes specific immunoglobulin M production. Deficiency of both MAVS and cGAS, or treatment of MAVS-deficient mice with reverse transcriptase inhibitors, dramatically inhibits TI-2 antibody responses. These findings suggest that ERV and two innate sensing pathways that detect them are integral components of the TI-2 B cell signaling apparatus.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391621/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391621/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Zeng, Ming -- Hu, Zeping -- Shi, Xiaolei -- Li, Xiaohong -- Zhan, Xiaoming -- Li, Xiao-Dong -- Wang, Jianhui -- Choi, Jin Huk -- Wang, Kuan-wen -- Purrington, Tiana -- Tang, Miao -- Fina, Maggy -- DeBerardinis, Ralph J -- Moresco, Eva Marie Y -- Pedersen, Gabriel -- McInerney, Gerald M -- Karlsson Hedestam, Gunilla B -- Chen, Zhijian J -- Beutler, Bruce -- P01 AI070167/AI/NIAID NIH HHS/ -- R01 AI093967/AI/NIAID NIH HHS/ -- R01 CA157996/CA/NCI NIH HHS/ -- U19 AI100627/AI/NIAID NIH HHS/ -- Howard Hughes Medical Institute/ -- New York, N.Y. -- Science. 2014 Dec 19;346(6216):1486-92. doi: 10.1126/science.346.6216.1486.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-8502, USA. ; Department of Pediatrics and Children's Medical Center Research Institute, and McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-8502, USA. ; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-8502, USA. Howard Hughes Medical Institute, Department of Molecular Biology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9148, USA. ; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Nobels vag 16, SE-171 77 Stockholm, Sweden. ; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-8502, USA. Bruce.Beutler@UTSouthwestern.edu.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/25525240" target="_blank"〉PubMed〈/a〉
    Keywords: Adaptor Proteins, Signal Transducing/genetics/*immunology ; Animals ; Antibody Formation ; Antigens, T-Independent/*immunology ; B-Lymphocytes/*immunology ; Cytosol/immunology ; DNA/immunology ; Endogenous Retroviruses/genetics/*immunology ; Lymphocyte Activation ; Membrane Proteins/immunology ; Mice ; Mice, Inbred C57BL ; NF-kappa B/metabolism ; Nucleotides, Cyclic/immunology ; Nucleotidyltransferases/genetics/*immunology ; RNA, Viral/genetics/*immunology ; Transcription, Genetic
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 6
    Publication Date: 2016-05-28
    Description: Author(s): Meng Wang, M. Yi, H. L. Sun, P. Valdivia, M. G. Kim, Z. J. Xu, T. Berlijn, A. D. Christianson, Songxue Chi, M. Hashimoto, D. H. Lu, X. D. Li, E. Bourret-Courchesne, Pengcheng Dai, D. H. Lee, T. A. Maier, and R. J. Birgeneau We report a combined study of the spin resonances and superconducting gaps for underdoped ( T c = 19 K), optimally doped ( T c = 25 K), and overdoped ( T c = 19 K) Ba ( Fe 1 − x Co x ) 2 As 2 single crystals with inelastic neutron scattering and angle resolved photoemission spectroscopy. We find a quasi-two-dimensional sp… [Phys. Rev. B 93, 205149] Published Thu May 26, 2016
    Keywords: Electronic structure and strongly correlated systems
    Print ISSN: 1098-0121
    Electronic ISSN: 1095-3795
    Topics: Physics
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 7
    Publication Date: 2015-11-10
    Description: The Handan-Xingtai district in the North China craton is one of the most important concentrations of iron skarn deposits in China, with proven reserves of 900 to 1,000 Mt at an average of 40 to 55 wt % Fe. The iron mineralization occurs predominantly along contact zones between Early Cretaceous intermediate-silicic intrusions and Middle Ordovician marine carbonates intercalated with numerous evaporite beds. In this paper, we present textural features and laser ablation ICP-MS U-Pb dating results of hydrothermal zircon from five major iron skarn deposits to place tight constraints on the timing and duration of the district-scale iron mineralization. Zircon grains from the mineralized skarns are anhedral to subhedral crystals and euhedral tetragonal bipyramids. They are closely intergrown or texturally associated with diopside, garnet, epidote, calcite, albite, and phlogopite. Other common minerals in the skarn assemblages include F-rich hornblende, wilkeite-F, F-apatite, and fluorite. Zircon grains typically contain abundant inclusions of skarn minerals and daughter mineral-rich (mostly magnetite, halite, and sylvite) fluid inclusions. Compositionally, these zircon grains have moderately to extremely high Th (518–7,477 ppm) and U (109–25,610 ppm) contents, with highly variable Th/U ratios ranging from 0.01 to 5.23. The morphological, textural, and geochemical features of the zircons confirm their hydrothermal origin and indicate that they most likely precipitated from high-temperature, F-rich, magmatic-derived ore-forming fluids. The hydrothermal zircon grains yield well-defined concordant U-Pb ages for the five studied iron skarn deposits, with weighted mean 206 Pb/ 238 U dates ranging from 133.6 ± 0.9 to 128.5 ± 1.4 Ma (2 ). These ages are remarkably consistent with U-Pb ages (134.1 ± 1.2 to 128.5 ± 0.9 Ma; 2 ) of magmatic zircon grains from the ore-related intrusions in each deposit, demonstrating that iron skarn mineralization was genetically related to the coeval magmatism. Our new geochronological data, when combined with existing isotopic ages, indicate that iron mineralization and associated magmatism in the Handan-Xingtai district took place mainly at the ca. 137–133 and 131–128 Ma intervals. Iron skarn deposits of similar ages also occur widely in other parts of the eastern North China craton, forming the only known giant Mesozoic iron skarn province in a cratonic block on the Earth. The formation of these iron skarn deposits and associated intrusions coincided in time with lithospheric thinning or destruction of the North China craton, strongly suggesting a causal link between the two processes.
    Print ISSN: 0361-0128
    Topics: Geosciences
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 8
    Publication Date: 2015-02-07
    Description: Two different confinement transition discharges, the low-intermediate-high (L-I-H) and the low-intermediate-low (L-I-L) confinement transitions, respectively, have been obtained by lower hybrid current drive with lithium wall conditioning in the EAST superconducting tokamak. The dynamic features of short-scale turbulent fluctuations in the two discharges are investigated by a tangential CO 2 laser collective scattering system. It is found that the great changes of broadband fluctuations in amplitude and structure characteristics are closely related to the choice of the final transition to H-mode. These results could shed light on the understanding of the L-H transition mechanism.
    Print ISSN: 1070-664X
    Electronic ISSN: 1089-7674
    Topics: Physics
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 9
    Publication Date: 2017-01-10
    Description: Trimethylation of histone H3K36 is a chromatin mark associated with active gene expression, which has been implicated in coupling transcription with mRNA splicing and DNA damage response. SETD2 is a major H3K36 trimethyltransferase, which has been implicated as a tumor suppressor in mammals. Here, we report the regulation of SETD2 protein stability by the proteasome system, and the identification of SPOP, a key subunit of the CUL3 ubiquitin E3 ligase complex, as a SETD2-interacting protein. We demonstrate that SPOP is critically involved in SETD2 stability control and that the SPOP/CUL3 complex is responsible for SETD2 polyubiquitination both in vivo and in vitro . ChIP-Seq analysis and biochemical experiments demonstrate that modulation of SPOP expression confers differential H3K36me3 on SETD2 target genes, and induce H3K36me3-coupled alternative splicing events. Together, these findings establish a functional connection between oncogenic SPOP and tumor suppressive SETD2 in the dynamic regulation of gene expression on chromatin.
    Print ISSN: 0305-1048
    Electronic ISSN: 1362-4962
    Topics: Biology
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 10
    Publication Date: 2014-09-27
    Description: X-ray photoelectron spectroscopy (XPS) was utilized to measure the valence band offset (Δ E V ) of the TiZnSnO (TZTO)/Si heterojunction. TZTO films were deposited on Si (100) substrates using magnetron sputtering at room temperature. By using the Zn 2 p 3/2 and Sn 3 d 5/2 energy levels as references, the value of Δ E V was calculated to be 2.69 ± 0.1 eV. Combining with the experimental optical energy band gap of 3.98 eV for TZTO extracted from the UV-vis transmittance spectrum, the conduction band offset (Δ E C ) was deduced to be 0.17 ± 0.1 eV at the interface. Hence, the energy band alignment of the heterojunction was determined accurately, showing a type-I form. This will be beneficial for the design and application of TZTO/Si hybrid devices.
    Print ISSN: 0021-8979
    Electronic ISSN: 1089-7550
    Topics: Physics
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...