ISSN:
1573-0646
Keywords:
hepatoma
;
merbarone
;
hepatocellular carcinoma
;
toxicity
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
,
Medicine
Notes:
Summary Sixteen eligible patients with hepatocellular carcinoma, previously untreated, received merbarone 1000 mg/ m2/d for five consecutive days every 21 days. No complete or partial response to treatment was obtained. Seven patients had grade 4 granulocytopenia. One patient died with renal failure. Merbarone in this dose and schedule was ineffective in the treatment of hepatocellular carcinoma.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00873051
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