ISSN:
1432-1327
Keywords:
Key words Chromium
;
Insulin receptor
;
Low-molecular-weight chromium-binding
;
substance
;
Diabetes
;
Glucose tolerance factor
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Chemistry and Pharmacology
Notes:
Abstract Since the discovery in the 1950s that mammals have a nutritional requirement for chromium, the biological function of chromium has been sought. Candidates for the naturally-occurring biologically active form of chromium have been proposed, but, until recently, all have been shown to be artifacts. Recent studies examining the properties of the oligopeptide low-molecular-weight chromium-binding substance (LMWCr) suggest that this material may have a role in carbohydrate and lipid metabolism as part of a novel insulin-signaling amplification mechanism and may have implications in the treatment of diabetes and related conditions.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s007750050183
Permalink
