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  • snow chemistry  (2)
  • sodium transport  (2)
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  • 1
    Digitale Medien
    Digitale Medien
    Effects of thyromimetric drugs on aldosterone-dependent sodium transport in the toad bladder (1984)
    Springer
    The journal of membrane biology 77 (1984), S. 15-23 
    Details
    ISSN: 1432-1424
    Schlagwort(e): aldosterone ; triidothyronine ; thyromimetic drugs ; sodium transport ; toad bladder ; Bufo marinus
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Chemie und Pharmazie
    Notizen: Summary Aldosterone increases transepithelial Na+ transport in the urinary bladder ofBufo marinus. The response is characterized by 3 distinct phases: 1) a lag period of about 60 min, ii) an initial phase (early response) of about 2 hr during which Na+ transport increases rapidly and transepithelial electrical resistance falls, and iii) a late phase (late response) of about 4 to 6 hr during which Na+ transport still increases significantly but with very little change in resistance. Triiodothyronine (T3, 6nm) added either 2 or 18 hr before aldosterone selectively antagonizes the late response. T3 per se (up to 6nm) has no effect on base-line Na+ transport. The antagonist activity of T3 is only apparent after a latent period of about 6 to 8 hr. It is not rapidly reversible after a 4-hr washout of the hormone. The effects appear to be selective for thyromimetic drugs since reverse T3 (rT3) is inactive and isopropyldiiodothyronine (isoT2) is more active than T3. The relative activity of these analogs corresponds to their relative affinity for T3 nuclear binding sites which we have previously described. Our data suggest that T3 might control the expression of aldosterone by regulating gene expression, e.g. by the induction of specific proteins, which in turn will inhibit the late mineralocorticoid response, without interaction with the early response.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01871096
    Standort Signatur Erwartet Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Effects of thyroid hormones and aldosterone on mineralocorticoid binding sites in the toad bladder (1984)
    Springer
    The journal of membrane biology 77 (1984), S. 25-32 
    Details
    ISSN: 1432-1424
    Schlagwort(e): aldosterone ; triiodothyronine ; sodium transport ; mineralocorticoid receptors ; bufo marinus ; down regulation
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Chemie und Pharmazie
    Notizen: Summary In the urinary bladder of the toadBufo marinus triiodothyronine selectively inhibits the late effect of aldosterone on Na+ transport. We have investigated whether T3 might mediate its antimineralocorticoid action by controlling: i) the level of aldosterone binding sites in the soluble (cytosolic) pool isolated from tissues treated with T3 (60nm) for up to 20 hr of incubation; ii) the kinetics of uptake of3H-aldosterone into cytoplasmic and nuclear fractions after 2 or 20 hr of exposure to T3. The number and the affinity of Type I (high affinity, low capacity) and Type II (low affinity, high capacity) cytosolic binding sites (measured at 0°C) did not vary significantly after 18 hr of exposure to T3, while aldosterone-dependent Na+ transport was significantly inhibited. In addition, T3 did not modify the kinetics of uptake (90 min) of3H-aldosterone into cytoplasmic and nuclear fractions of toad bladder incubatedin vitro at 25°C. By contrast, aldosterone itself was able to down-regulate its cytosolic and nuclear binding sites after an 18-hr exposure to the steroid hormone (10 or 80nm). T3 slightly (20%) but significantly potentiated the down regulation of nuclear binding sites. In conclusion, T3 does not appear to have major effects on the regulation of the aldosterone receptor, which could explain in a simple manner its antimineralocorticoid action.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01871097
    Standort Signatur Erwartet Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    Intercomparison of snow Sampling and Analysis Within the Alpine-Wide Snowpack Investigation (SNOSP) (1997)
    Springer
    Water, air & soil pollution 93 (1997), S. 67-91 
    Details
    ISSN: 1573-2932
    Schlagwort(e): Snow sampling ; snow chemistry ; intercomparison ; Alps
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Energietechnik
    Notizen: Abstract In order to investigate the seasonal and geographical distribution of snow concentrations anddeposition fluxes of environmentally relevant ionic species in the Alps, the international programSNOSP was initiated. In the framework of this program, intercomparisons of snow samplingtechniques and analytical methods to determine the ionic species C1-, NO 3 - ,SO 4 2- , K+, Na+, NH4 +, Mg2+, and Ca2+, as well as the pH and the specificconductivity were performed. The concentrations of these species in the snow samples collectedin the SNOSP program varied by orders of magnitude with, e.g., concentrations of NO 3 - , SO 4 2- , and NH4 + ranging from 0.2-60, 0.2-90, and 0.1-60 µeq L-1,respectively. The intercomparisons revealed a reasonable agreement of the determinations of thespecies Cl-, NO 3 - , SO 4 2- , Na+, and NH4 + in snow. Results were less satisfactory for K+, Mg2+, Ca2+,and H+, mainly due to the very low concentrations. In conclusion, recommendations areformulated for the reliable derivation of chemical inventories from snow packs.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1023/A:1022167507380
    Standort Signatur Erwartet Verfügbarkeit
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  • 4
    Digitale Medien
    Digitale Medien
    Intercomparison of snow sampling and analysis within the alpine-wide snowpack investigation (SNOSP) (1997)
    Springer
    Water, air & soil pollution 93 (1997), S. 67-91 
    Details
    ISSN: 1573-2932
    Schlagwort(e): Snow sampling ; snow chemistry ; intercomparison ; Alps
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Energietechnik
    Notizen: Abstract In order to investigate the seasonal and geographical distribution of snow concentrations and deposition fluxes of environmentally relevant ionic species in the Alps, the international program SNOSP was initiated. In the framework of this program, intercomparisons of snow sampling techniques and analytical methods to determine the ionic species Cl−, NO3 −, SO4 2−, K+, Na+, NH4 +, Mg2+, and Ca2+, as well as the pH and the specific conductivity were performed. The concentrations of these species in the snow samples collected in the SNOSP program varied by orders of magnitude with, e.g., concentrations of NO3 −, SO4 2−, and NH4 + ranging from 0.2–60, 0.2–90, and 0.1–60μeq L−1, respectively. The intercomparisons revealed a reasonable agreement of the determinations of the species Cl−, NO3 −, SO4 2−, Na+, and NH4 + in snow. Results were less satisfactory for K+, Mg2+, Ca2+, and H+, mainly due to the very low concentrations. In conclusion, recommendations are formulated for the reliable derivation of chemical inventories from snow packs.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02404748
    Standort Signatur Erwartet Verfügbarkeit
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