ISSN:
1573-4927
Keywords:
protease inhibitors
;
fungal protease
;
chymotrypsin
;
genetic variants
;
silkworm
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Chemistry and Pharmacology
Notes:
Abstract Many electrophoretic variants of hemolymph inhibitors of proteases from Aspergillus mellus and pancreatic α-chymotrypsin were found using 126 silkworm strains. Six inhibitors of the fungal protease were detected and eight of chymotryspin; the distribution of inhibitors among Japanese, Chinese, and European races was investigated. Comparison of electrophoretic patterns from F1 hybrids and parents showed that the offspring produce inhibitors of both parental types. Segregation in F2 and backcrossing suggest that the expression of each inhibitor is controlled in most cases by a pair of alleles which are responsible for strong and null bands. Two bands of fungal protease inhibitors C and D were controlled by codominant alleles. These results suggest that polymorphism of hemolymph protease inhibitors in the silkworm would be a useful experimental system for the study of the genetic control of protease inhibitors.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00499634
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