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  • 1
    Electronic Resource
    Electronic Resource
    The Pharmacokinetics of Trilostane and Ketotrilostane in an Interconverting System in the Rat (1992)
    Springer
    Pharmaceutical research 9 (1992), S. 464-468 
    Details
    ISSN: 1573-904X
    Keywords: trilostane ; ketotrilostane ; reversible metabolism ; pharmacokinetics ; metabolic interconversion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract The pharmacokinetics of trilostane and one of its metabolites ketotrilostane are described and characterized in the rat following the separate intravenous administration of trilostane and ketotrilostane. It was noted during these studies that the parent compound and its metabolite undergo metabolic interconversion–trilostane producing ketotrilostane and ketotrilostane generating trilostane. This result means that trilostane is conserved in the body by interconversion-being metabolized to ketotrilostane and then subsequently back to the “parent” drug, trilostane.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1015828027060
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    Paper (German National Licenses)
    Fulltext
  • 2
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    Unknown
    Fluids management technology (1982)
    In:  CASI
    Details
    Publication Date: 2016-06-07
    Description: Various techniques and methods in fluid management are discussed. Propellant on-orbit transfer efficiency from the space shuttle orbiter to orbital transfer vehicle is discussed. Techniques such as refueling, residuals recovery and propellant storage are described.
    Keywords: SPACE TRANSPORTATION
    Type: Satellite Serv. Workshop, Vol. 1; p 381-405
    Format: application/pdf
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    NASA TECHNICAL REPORTS
  • 3
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    Evaluation of thermal insulation materials (1973)
    In:  CASI
    Details
    Publication Date: 2019-06-27
    Description: Data was obtained on silicone-bonded fiberglass, isocyanurate foam, and two dozen other insulators. Materials were selected to withstand heat sterilization, outer space, and the Martian atmosphere. Significant environmental parameters were vibration, landing shock, and launch venting.
    Keywords: MATERIALS
    Type: NPO-11586
    Format: application/pdf
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    NASA TECHNICAL REPORTS
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