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Stereoselection in designed three-helix bundle metalloproteins (1998)

Case, Martin A. ; Ghadiri, M. Reza ; Mutz, Mitchell W. ; [et al.]

New York, NY [u.a.] : Wiley-Blackwell

Chirality 10 (1998), S. 35-40

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ISSN: 0899-0042

Keywords: de novo design ; self-assembly ; metalloproteins ; diastereoselection ; Chemistry ; Organic Chemistry

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Chemistry and Pharmacology

Notes: The stereochemical consequences of the metal-ion assisted self-assembly of parallel three-helix peptide bundles are investigated. Chiral induction in the self-assembly of systems containing extensive protein secondary structure is compared with the racemic synthesis of short metallopeptides. Isolation and characterization of the individual stereoisomers of an exchange-inert metalloprotein provide structural insights into analogous exchange-labile systems. Chirality 10:35-40, 1998. © 1998 Wiley-Liss,Inc.

Additional Material: 6 Ill.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1002/chir.7

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