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  • erosion  (1)
  • liver  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Isolation, characterization, and determination of human liver (copper/zinc) metallothionein (1990)
    Springer
    Cellular and molecular life sciences 46 (1990), S. 688-693 
    Details
    ISSN: 1420-9071
    Keywords: Metallothionein ; liver ; primary biliary cirrhosis ; copper ; zinc
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary A copper-containing protein was purified from the liver of a patient with primary biliary cirrhosis by a combination of gel filtration and anion exchange chromatography. This copper-protein had UV absorption and emission spectra, an amino acid composition, and a molecular mass which were characteristic for metallothionein (MT). From 8 livers (3 control, 1 fetal and 4 primary biliary cirrhosis) MT was extracted with non-reducing buffer and centrifuged, and the pellets were re-extracted with a 1% 2-mercaptoethanol-containing buffer. The non-reducing buffer extracted a predominantly copper-containing MT from the livers of patients with primary biliary cirrhosis and a predominantly zinc-containing MT from control lives and the fetal liver. Only from the fetal liver was a copper/zinc containing MT solubilized during the re-extraction with 2-mercaptoethanol-containing buffer. These results indicate that human MT is a unique metalloprotein with age and disease-dependent characteristics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01939936
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  • 2
    Electronic Resource
    Electronic Resource
    Paleolimnology of Slapton Ley, Devon, UK (1991)
    Springer
    Hydrobiologia 214 (1991), S. 115-124 
    Details
    ISSN: 1573-5117
    Keywords: paleolimnology ; 210Pb dating ; magnetic susceptibility ; core correlation ; erosion ; diatom analysis ; chlorophyll a ; eutrophication
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Slapton Ley, a coastal lake in SW England, has been shown by a variety of paleolimnological studies, to have become increasingly eutrophic in the period since 1950 AD. Since that time, intensification of agriculture has resulted in increased erosion of topsoil from fields in the catchment of the Ley. Sediment accumulation rates, as estimated by 210Pb-dating and multiple core correlation of peaks in whole core volume magnetic susceptibility, are equivalent to a catchment erosion rate of 13.4 t km−2 a−1, which figure agrees well with directly monitored data. Diatom and chlorophyll a analysis of the uppermost sediments shows that the Ley has recently experienced a major shift in its trophic status, changing from a clear water, macrophyte lake to one dominated by plankton in a hypertrophic system. This last point is further amplified in the paper by Heathwaite & O'Sullivan (1991).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00050940
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