ISSN:
1432-1041
Keywords:
ibopamine
;
prolactin
;
aldosterone
;
inhibition of secretion
;
congestive heart failure
;
growth hormone
;
cortisol
;
metoclopramide
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
,
Medicine
Notes:
Summary In 7 patients with congestive heart failure acute oral administration of ibopamine, a new dopamine derivative, induced a significant decrease in serum prolactin and aldosterone without affecting serum growth hormone or cortisol. The Metoclopramide-induced secretion of prolactin and aldosterone was blunted in 6 patients pretreated with 200 mg ibopamine. The data are consistent with a dopaminergic effect of ibopamine due to a peripheral action, probably on D-2 receptors.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00635905
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