ISSN:
1573-1111
Keywords:
1,8-Anilinonaphthalene sulfonic acid (1,8-ANS)
;
binding strength, complex constants
;
cyclodextrins
;
fluorescence measurements
;
host/guest complex chemistry
;
macro-(mono/bi-)cyclic compounds
;
synthetic hosts, lactams
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract It is shown that the synthetic host compounds described in this study possess higher complexation constants versus 1,8-ANS than β-or γ-cyclodextrin. The attachment of side chains to β-cyclodextrin increases the complex formation, whereas the value of γ-cyclodextrin is not reached. The quaternary ammonium nitrogens of the synthetic hosts may be replaced by amide groups without diminution of the association constants. Bicyclic compounds in general bind more strongly than monocyclic hosts due to tighter inclusion and increased hydrophobic interaction. The influence of side chains attached to synthetic host compounds on the complexation constants is difficult to predict.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00657499
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