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Hepatoma/merbarone (1994)

Poplin, Elizabeth A. ; Tangen, Catherine M. ; Harvey, Walter H. ; [et al.]

Springer

Investigational new drugs 12 (1994), S. 337-340

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ISSN: 1573-0646

Keywords: hepatoma ; merbarone ; hepatocellular carcinoma ; toxicity

Source: Springer Online Journal Archives 1860-2000

Topics: Chemistry and Pharmacology , Medicine

Notes: Summary Sixteen eligible patients with hepatocellular carcinoma, previously untreated, received merbarone 1000 mg/ m2/d for five consecutive days every 21 days. No complete or partial response to treatment was obtained. Seven patients had grade 4 granulocytopenia. One patient died with renal failure. Merbarone in this dose and schedule was ineffective in the treatment of hepatocellular carcinoma.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00873051

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