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  • Na2SO4 melt  (1)
  • frusemide  (1)
  • 1980-1984  (2)
  • 1960-1964
  • 1930-1934
  • 1
    Electronic Resource
    Electronic Resource
    Variance comparison as a tool in clinical pharmacology: An example with two loop diuretics (1982)
    Springer
    European journal of clinical pharmacology 23 (1982), S. 221-224 
    Details
    ISSN: 1432-1041
    Keywords: frusemide ; piretanide ; variance comparison ; regularity of effect ; activity comparison ; drug excretion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Comparison of variances can be useful in assessing the regularity of drug effects. In order to compare the variances of the saluretic effects of piretanide and frusemide, two loop diuretics with different bioavailabilities, a double-blind cross-over study was carried out in 34 normal volunteers. The diuretics were given in randomized order, with an interval of 7 days, in single equipotent doses (frusemide 6.25 mg and piretanide 1.0 mg chosen from previous results) adjusted by body weight. The dispersion of individual values (comparison of variances from paired measures) for Na+, Cl− and Ca++ excretion, urine osmolality and excretion of the drugs, was significantly smaller for piretanide than for frusemide. It is concluded that the saluretic effect of a single dose of piretanide varies less than that of an equipotent dose of frusemide. The methodology may be useful in trials of drugs for which regularity of effect is important.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00547557
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  • 2
    Electronic Resource
    Electronic Resource
    The identification of the sulfide NaCrS2 in nickel-base superalloys during corrosion in sulfate melts (1982)
    Springer
    Oxidation of metals 18 (1982), S. 187-194 
    Details
    ISSN: 1573-4889
    Keywords: Sulfide NaCrS2 ; basic fluxing ; nickel-base superalloy ; Na2SO4 melt
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The sulfide NaCrS2 has been identified in the internal corrosion zone of several nickel-base superalloys under basic fluxing conditions at very negative potentials in a 90% Na2SO4-10% K2SO4 melt at 1173 K. It can also be formed in the presence of carbon-contaminated sulfate. NaCrS2 can dissolve some Ti, Al, Ni, and Co; other elements, e.g., K, Mo, W, Nb, Ta, and Zr, could not be detected.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00662037
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