ISSN:
1572-9001
Keywords:
Crystal engineering
;
hydrogen bonding
;
inclusion
;
(O — H)6 cycle
;
ethanol
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract The cage compound 4,7-dimethylpentacyclo[6.3.0.02,6.03,10.05,9]undecane-anti-4,anti-7-diol 3 and its 4,7-bis(d 3-methyl) derivative 4 form 1:1 cocrystalline complexes with ethanol instead of the expected helical tubulate inclusion compounds. The X-ray crystal structure of (4)·(ethanol) [(C13H12D6O2)·(C2H6O), Cmca, a 19.049(2), b 14.932(2), c 10.117(1) Å, Z 8, R 0.061] shows that the key supramolecular synthon is a hydrogen-bonded (O — H)6 cycle of hydroxy groups constructed from two ethanols (in ring positions 1 and 4) and four diols. This uncommon centrosymmetric motif permits efficient lattice packing of ethanol and both diol enantiomers into layers without requiring the self-resolution that would be mandatory in forming the helical tubulate structure.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1023/A:1021880328629
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