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  • 1
    Electronic Resource
    Electronic Resource
    Complex Analysis of Efficiency of Transplantation of Embryonic Nerve Tissue to Rats with Hemiparkinsonism (2000)
    Springer
    Bulletin of experimental biology and medicine 130 (2000), S. 1181-1185 
    Details
    ISSN: 1573-8221
    Keywords: 6-OHDA-induced hemiparkinsonism ; embryonic nerve tissue transplantation ; dopamine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Effect of transplantation of embryonic ventral mesencephalon preparation containing dopaminergic neurons on repair of the dopaminergic nigrostriatal system was studied in rats with hemiparkinsonism induced by 6-hydroxydopamine. Transplantation of embryonic ventral mesencephalon into denervated striatum led to a more than 50% decrease in apomorphine-induced rotation, recovery of dopamine and DOPAC levels in the brain, and to an increase in DOPAC excretion and the DOPAC-dopamine ratio in daily urine of rats with hemiparkinsonism. Dopaminergic neurons of the transplant survived, forming a network of tyrosine hydroxylase-positive processes growing beyond the transplant and reinnervating the adjacent compartments of the striatum. A positive correlation between urinary excretion of DOPAC and brain concentration of dopamine was revealed in denervated rats after transplantation of ventral mesencephalon. Intrastriatal transplantation of cell preparations of embryonic striatum containing no dopaminergic neurons and isolated local injury to the striatum did not affect regeneration of the denervated nigrostratal system.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1017588119655
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  • 2
    Electronic Resource
    Electronic Resource
    Magnetic shielding of the brain in the vertebrates (1998)
    Springer
    Bulletin of experimental biology and medicine 126 (1998), S. 1251-1253 
    Details
    ISSN: 1573-8221
    Keywords: venous collectors ; magnetic shielding ; defense and adaptive reactions ; corticosteroids
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract A model of magnetic shielding of the brain and spinal cord in the vertebrates has been suggested. Endogenous magnetic field in this model is formed at the expense of directed transposition of charged blood erythrocytes in the circular venous collectors involving various compartments of the central nervous system. Detected changes in the levels of corticosteroids, erythrocyte count, blood viscosity, hematocrit, and clotting system during exposure to a magnetic field indicate that magnetic shielding is part of the defense and adaptive reaction complex.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02447166
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