ISSN:
1573-3904
Keywords:
coumarin amino acid
;
fluorogenic substrate
;
proteinase
;
solid-phase synthesis
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract A high-yielding synthesis of the highly fluorescent amino acid l-2-amino-3-(7-methoxy-4-coumaryl)propionic acid (l-Amp) has been developed via (2R)-bornane-10,2-sultam glycinate. l-Amp facilitates the synthesis of sensitive fluorogenic proteinase substrates with N-terminal solubilising or reactive groups.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1023/A:1008856226362
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