ISSN:
1573-1111
Keywords:
Chiral crown ethers
;
complex formation
;
glucuronic acids
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract Crown ethers1 and4 of the 18-crown-6 type containing two glucose units have been oxidised by KMnO4 into mono- and dicarboxylic acid derivatives (5 and11), and derivatives with different lipophilicities of the above crown ethers, namely the acetyl, benzyl and butyl derivatives (8–10, 13, 14) and methyl esters (6 and12) have been synthesized The association constants (K a) with Li, Na, K and NH4 cations measured in CHCl3 indicate that complexing ability increases on introduction of carboxy groups, and selectivity changes in favour of the Na cation. These compounds were able to transport alkyl-ammonium salts through a CHCl3 liquid membrane, displaying, however, no chiral recognition ability.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01053549
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