ISSN:
1573-1111
Keywords:
Cyclodextrin
;
ethyl viologen
;
binding ability
;
conformation
;
steroidal guest
;
complex
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract The conformational and binding properties of mono-6-deoxy-6[4-(1-ethyl-4-pyridinio)-1-pyridinio]-β-cyclodextrin (1) in complex formation with some guest compounds were examined by induced circular dichroism (ICD) spectra in aqueous solution. Compound 1 showed much stronger binding ability for some guest compounds (1: 1 complexes), compared withβ-cyclodextrin (β-CDx) and a positively charged β-CDx [C-6-mono-pyridino-β-CDx (2)]. Marked conformational changes of1 (the spatial position of the ethyl viologen (C2V2+) group relative to the cavity in 1) were observed upon complex formation with some guests like 1-adamantanecarboxylic acid (ACA) and sodium cholate (SC).
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01061075
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