ISSN:
1573-3297
Keywords:
Twins
;
stuttering
;
speech disorders
;
bivariate analysis
;
ascertainment bias
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Psychology
Notes:
Abstract Stuttering is a developmental disorder of speech production that usually emerges in childhood. In this study, a large population-based twin sample from the Australian Twin Registry (1567 pairs and 634 singles aged 17–29 years) was screened to identify twin pairs in which one or both members reported themselves to be affected by stuttering. Telephone interview-based diagnoses were obtained for 457 of these individuals (self-reported affected cases, cotwins, and controls) to determine whether the self-report was correct. To correct for ascertainment bias we carried out a bivariate analysis of the final diagnosis in the selected sample with the screening item in the full sample, using the categorical raw data option of Mx 1.47c. After correcting for ascertainment bias, approximately 70% (95% confidence interval: 39–86%) of the variance in liability to stuttering was found to be attributable to additive genetic effects, with the remainder due to nonshared environmental effects.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1023/A:1002765620208
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