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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of aquatic ecosystem stress and recovery 1 (1973), S. 135-146 
    ISSN: 1573-5141
    Keywords: carcinogens ; cancer ; biomarker
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Evidence has linked toxicants in aquatic systems with cancer in fish and population level effects on species. Thus some types of tumors may be useful monitors of ecosystem health, at least as affected by genotoxins and promoters. However, tumors caused by purely genetic mechanisms or by virus would not be good indicators. Only neoplasms which have chemicals as a portion of their etiology (either as initiators or promoters) would be useful in assessing ecosystem health. Lesions which may fit these criteria include liver neoplasms (both biliary and hepatic) and skin lesions in a variety of primarily benthic fishes, and neural lesions in various drum species and in butterfly fish species. Two studies purporting to demonstrate a lack of tumors in fish from polluted areas have been reexamined and found either to have insufficient data on vulnerable species or to actually support a tumor-pollution linkage. Thus certain lesions in vulnerable species or species groups may serve as a mechanism to assess one facet of ecosystem health.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of aquatic ecosystem stress and recovery 1 (1973), S. 127-133 
    ISSN: 1573-5141
    Keywords: carcinogens ; cancer ; biomarker ; monitoring
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The usefulness of tumor surveys in indicating the availability of carcinogenic contaminants in ecosystems hinges largely on decisions made during the planning process. Species used as indicator organisms for monitoring programs are best selected from those known to be susceptible to epizootics of neoplasms. Lesions which can be quickly located and preserved in the field and for which a data base exists to help interpretation include liver neoplasms and external neoplasms. Since tumor frequencies increase with age and may change from season to season, studies should hold these variables constant among locations. During the design of the study investigators should determine the number of fish they need to examine in order to achieve the degree of resolution desired. Finally the field crew must be familiar with fish anatomy and necropsy techniques as well as storage and handling of the chosen preservative.
    Type of Medium: Electronic Resource
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