Publication Date:
2014-01-08
Description:
The four-component reaction of 2-aminobenzothiazole, aromatic aldehydes, acetylenedicarboxylate and piperidine or pyrrolidine in ethanol afforded the functionalized 2-pyrrolidinones containing both benzothiazolyl and piperidinyl (or pyrrolidinyl) units in good yields. On the other hand, the similar four-component reactions resulted in the functionalized morpholinium or piperidinium 2-pyrrolidinon-3-olates in the presence of p -toluenesulfonic acid. Beilstein J. Org. Chem. 2013, 9, 2934–2939. doi:10.3762/bjoc.9.330
Keywords:
benzothiazoledomino reactionelectron-deficient alkynemulticomponent reactionpyrrolidinone
Electronic ISSN:
1860-5397
Topics:
Chemistry and Pharmacology
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