ISSN:
1573-6849
Keywords:
high-resolution
;
fluorescence
;
in situ hybridization
;
spermatogenesis genes
;
Y chromosome evolution
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Abstract Applying two-colour fluorescencein situ hybridization (FISH) we simultaneously hybridizedRBM- andTSPY-related cosmids to Y chromosomes in prophase and to released Y chromatin in interphase nuclei of man and pygmy chimpanzee. Whereas, even on prophasic Y chromosomes, no resolution of the overlappingRBM andTSPY signal clusters could be achieved, theRBM andTSPY signals are completely separated from each other in our maximum released Y chromatin stretches in interphase nuclei. These results unequivocally lend support to the view that theRBM andTSPY families have an interspersed organization on the Y chromosomes of man and higher apes. Thus, the distribution ofRBM andTSPY signals might well go back to a common organization of these genes next to each other on an ancient Y chromosome.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02254960
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