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  • 1
    Electronic Resource
    Electronic Resource
    A murine TSPY (1998)
    Springer
    Chromosome research 6 (1998), S. 35-40 
    Details
    ISSN: 1573-6849
    Keywords: murine TSPY ; Y chromosome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Sequences homologous to human and bovine TSPY were isolated from M. musculus testicular cDNA, and a nearly full-length gene was polymerase chain reaction (PCR) amplified from mouse genomic DNA. This gene is apparently non-functional. Contrary to the situation encountered in species along the primate and artiodactyl lineages, in which TSPY is moderately repetitive, murine Tspy appears to be single copy. Murine Tspy is located on Yp, i.e. in the same syntenic group as in man. Sequence comparisons of murine, human and bovine TSPY exons suggest that TSPY became non-functional during rodent evolution.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1009214307764
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  • 2
    Electronic Resource
    Electronic Resource
    Loss of telomeric sites in the chromosomes ofMus musculus domesticus (Rodentia: Muridae) during Robertsonian rearrangements (1995)
    Springer
    Chromosome research 3 (1995), S. 399-409 
    Details
    ISSN: 1573-6849
    Keywords: minor satellite DNA ; Mus ; Robertsonian rearrangements ; telomeres ; Y chromosome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Mouse chromosomes possessing multiple Robertsonian rearrangements (Rb chromosomes) have been examined using fluorescencein situ hybridization with the telomeric consensus sequence (TTAGGG)n. No hybridization signals were detected at the primary constriction of Rb chromosomes. This observation leads us to conclude that the formation of Rb chromosomes in the mouse is invariably associated with the loss of telomeric regions. More significantly, a further alteration in regions flanking the primary constrictions was observed after hybridizing with a minor satellite DNA probe to Rb chromosomes. It seems likely that the breakpoints required for a Robertsonian process do not include telomeric sites exclusively but extend to the adjacent pericentromeric regions of the original acrocentric chromosomes. In contrast to previous reports, these observations demonstrate the elimination of substantial amounts of chromosomal DNA during the formation of mouse Rb chromosomes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00713889
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    Paper (German National Licenses)
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