Publikationsdatum:
2011-12-21
Beschreibung:
“Two independent groups of investigators have found evidence of an enzyme… which synthesizes DNA from an RNA template. This discovery, if upheld, will have important implications… information transfer from DNA to RNA can be inverted.” 1970, preamble to refs. 1 and 2.These words accompanied two articles describing the discovery of RNA-dependent DNA polymerase, now known as reverse transcriptase (RT), in the virions of RNA tumor viruses. RT activity was recognized independently by David Baltimore (1) and Howard Temin and Satoshi Mizutani (2). In five printed pages these authors collectively challenged the unidirectionality of macromolecular synthesis, from DNA to RNA to...
Schlagwort(e):
Telomerase and Retrotransposons: Reverse Transcriptases That Shaped Genomes Sackler Special Feature
Print ISSN:
0027-8424
Digitale ISSN:
1091-6490
Thema:
Biologie
,
Medizin
,
Allgemeine Naturwissenschaft
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