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  • 1
    Electronic Resource
    Electronic Resource
    Ophthalmic fluorophotometry: an improved slit-lamp fluorophotometer (1979)
    Springer
    Medical & biological engineering & computing 17 (1979), S. 365-370 
    Details
    ISSN: 1741-0444
    Keywords: Fluorophotometer ; Ophthalmology ; Tear turnover
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract The use of fluorescein dye for the study of ocular dynamics in ophthalmology is briefly reviewed. General principles for designing objective fluorophotometers for measuring the rate of change of fluorescein concentration are discussed. Details of the circuitry and performance of a new improved objective fluorophotometer using a quartz-halogen excitation source and a synchronous detector are presented. In a preliminary clinical trial the mean tear turnover rate for ten normal subjects was found to be 21±13% min−1.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02443824
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Continuous fluorophotometric method of measuring tear turnover rate in humans and analysis of factors affecting accuracy (1986)
    Springer
    Medical & biological engineering & computing 24 (1986), S. 386-392 
    Details
    ISSN: 1741-0444
    Keywords: Tear turnover ; Fluorophotometry ; Ophthalmology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract An improved continuous reading fluorophotometer with provision for controlling the blink rate has been used to measure tear turnover rates in 14 normal healthy volunteers. A significant difference between morning and afternoon tear turnover results has been found, indicating a possible circadian rhythm in tear flow. Sources of potential systematic error in the measurement method have been identified and analysed. Fluorescence measurements using a thin film cell have confirmed predictions of nonlinearity in fluorophotometer output at high tear film concentrations. The error in tear film fluorescence due to diffusion of fluorescein into the cornea has also been investigated. Simple precautions to minimise these errors are suggested, which should make the measurement method suitable for clinical application.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02442693
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  • 3
    Electronic Resource
    Electronic Resource
    Pupillometer for clinical applications using dual 256-element linear CCD arrays (1992)
    Springer
    Medical & biological engineering & computing 30 (1992), S. 487-490 
    Details
    ISSN: 1741-0444
    Keywords: Charge-coupled device ; Infra-red ; Pupillometer
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract A new pupillometer for measuring the size of the pupil of the human eye is described. It uses two inexpensive 256-element charge coupled device (CCD) arrays in an orthogonal configuration. The system is controlled and data are analysed by means of a Z80A microcomputer. Software allows the position and diameter of the pupil to be displayed on a monochrome video monitor. Infra-red diodes irradiate the eye so that measurements can be made in darkness. The accuracy is better than ±0·1 mm, over the range 3·2–9·5 mm. Dynamic measurements of the pupil light reflex response can be made with sampling periods as short as 20 ms.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02457826
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    Paper (German National Licenses)
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