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  • 1
    Publication Date: 2002-04-06
    Description: The genome of the japonica subspecies of rice, an important cereal and model monocot, was sequenced and assembled by whole-genome shotgun sequencing. The assembled sequence covers 93% of the 420-megabase genome. Gene predictions on the assembled sequence suggest that the genome contains 32,000 to 50,000 genes. Homologs of 98% of the known maize, wheat, and barley proteins are found in rice. Synteny and gene homology between rice and the other cereal genomes are extensive, whereas synteny with Arabidopsis is limited. Assignment of candidate rice orthologs to Arabidopsis genes is possible in many cases. The rice genome sequence provides a foundation for the improvement of cereals, our most important crops.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Goff, Stephen A -- Ricke, Darrell -- Lan, Tien-Hung -- Presting, Gernot -- Wang, Ronglin -- Dunn, Molly -- Glazebrook, Jane -- Sessions, Allen -- Oeller, Paul -- Varma, Hemant -- Hadley, David -- Hutchison, Don -- Martin, Chris -- Katagiri, Fumiaki -- Lange, B Markus -- Moughamer, Todd -- Xia, Yu -- Budworth, Paul -- Zhong, Jingping -- Miguel, Trini -- Paszkowski, Uta -- Zhang, Shiping -- Colbert, Michelle -- Sun, Wei-lin -- Chen, Lili -- Cooper, Bret -- Park, Sylvia -- Wood, Todd Charles -- Mao, Long -- Quail, Peter -- Wing, Rod -- Dean, Ralph -- Yu, Yeisoo -- Zharkikh, Andrey -- Shen, Richard -- Sahasrabudhe, Sudhir -- Thomas, Alun -- Cannings, Rob -- Gutin, Alexander -- Pruss, Dmitry -- Reid, Julia -- Tavtigian, Sean -- Mitchell, Jeff -- Eldredge, Glenn -- Scholl, Terri -- Miller, Rose Mary -- Bhatnagar, Satish -- Adey, Nils -- Rubano, Todd -- Tusneem, Nadeem -- Robinson, Rosann -- Feldhaus, Jane -- Macalma, Teresita -- Oliphant, Arnold -- Briggs, Steven -- New York, N.Y. -- Science. 2002 Apr 5;296(5565):92-100.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Torrey Mesa Research Institute, Syngenta, 3115 Merryfield Row, San Diego, CA 92121, USA. stephen.goff@syngenta.com〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/11935018" target="_blank"〉PubMed〈/a〉
    Keywords: Arabidopsis/genetics ; Chromosome Mapping ; Chromosomes/genetics ; Computational Biology ; Conserved Sequence ; DNA, Plant/genetics ; Databases, Nucleic Acid ; Edible Grain/genetics ; Gene Duplication ; Genes, Plant ; *Genome, Plant ; Genomics ; Oryza/*genetics/metabolism/physiology ; Phosphate Transport Proteins/genetics ; Plant Diseases ; Plant Proteins/chemistry/genetics ; Plant Structures/genetics ; Repetitive Sequences, Nucleic Acid ; *Sequence Analysis, DNA ; Sequence Homology, Nucleic Acid ; Software ; Synteny ; Transcription Factors/genetics
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 2
    Publication Date: 2002-07-27
    Description: The compact genome of Fugu rubripes has been sequenced to over 95% coverage, and more than 80% of the assembly is in multigene-sized scaffolds. In this 365-megabase vertebrate genome, repetitive DNA accounts for less than one-sixth of the sequence, and gene loci occupy about one-third of the genome. As with the human genome, gene loci are not evenly distributed, but are clustered into sparse and dense regions. Some "giant" genes were observed that had average coding sequence sizes but were spread over genomic lengths significantly larger than those of their human orthologs. Although three-quarters of predicted human proteins have a strong match to Fugu, approximately a quarter of the human proteins had highly diverged from or had no pufferfish homologs, highlighting the extent of protein evolution in the 450 million years since teleosts and mammals diverged. Conserved linkages between Fugu and human genes indicate the preservation of chromosomal segments from the common vertebrate ancestor, but with considerable scrambling of gene order.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Aparicio, Samuel -- Chapman, Jarrod -- Stupka, Elia -- Putnam, Nik -- Chia, Jer-Ming -- Dehal, Paramvir -- Christoffels, Alan -- Rash, Sam -- Hoon, Shawn -- Smit, Arian -- Gelpke, Maarten D Sollewijn -- Roach, Jared -- Oh, Tania -- Ho, Isaac Y -- Wong, Marie -- Detter, Chris -- Verhoef, Frans -- Predki, Paul -- Tay, Alice -- Lucas, Susan -- Richardson, Paul -- Smith, Sarah F -- Clark, Melody S -- Edwards, Yvonne J K -- Doggett, Norman -- Zharkikh, Andrey -- Tavtigian, Sean V -- Pruss, Dmitry -- Barnstead, Mary -- Evans, Cheryl -- Baden, Holly -- Powell, Justin -- Glusman, Gustavo -- Rowen, Lee -- Hood, Leroy -- Tan, Y H -- Elgar, Greg -- Hawkins, Trevor -- Venkatesh, Byrappa -- Rokhsar, Daniel -- Brenner, Sydney -- New York, N.Y. -- Science. 2002 Aug 23;297(5585):1301-10. Epub 2002 Jul 25.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Institute of Molecular and Cell Biology, 30 Medical Drive, Singapore 117609. saa1000@cam.ac.uk〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/12142439" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Biological Evolution ; Computational Biology ; Conserved Sequence ; DNA Transposable Elements ; Evolution, Molecular ; Exons ; Fish Proteins/chemistry/genetics ; Gene Duplication ; Gene Order ; *Genome ; *Genome, Human ; Genomics ; Humans ; Introns ; Physical Chromosome Mapping ; Proteins/chemistry/genetics ; Proteome ; Repetitive Sequences, Nucleic Acid ; *Sequence Analysis, DNA ; Synteny ; Takifugu/*genetics
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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