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  • 1
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    Local structure, pseudosymmetry, and phase transitions in Na_{1/2}Bi_{1/2}TiO_{3}–K_{1/2}Bi_{1/2}TiO_{3} ceramics (2013)
    American Physical Society (APS)
    Details
    Publication Date: 2013-02-01
    Description: Author(s): I. Levin, I. M. Reaney, E-M. Anton, Wook Jo, J. Rödel, J. Pokorny, L. A. Schmitt, H-J. Kleebe, M. Hinterstein, and J. L. Jones The structural behavior of ceramic solid solutions (1− x )Na 1/2 Bi 1/2 TiO 3 – x K 1/2 Bi 1/2 TiO 3 (NBT-KBT) was studied using high-resolution powder diffraction and transmission electron microscopy. A temperature-independent morphotropic phase boundary (MPB) separating NBT-like pseudorhombohedral (R) and KBT-li... [Phys. Rev. B 87, 024113] Published Thu Jan 31, 2013
    Keywords: Structure, structural phase transitions, mechanical properties, defects
    Print ISSN: 1098-0121
    Electronic ISSN: 1095-3795
    Topics: Physics
    Published by American Physical Society (APS)
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  • 2
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    Anomalous reduction in domain wall displacement at the morphotropic phase boundary of the piezoelectric alloy system PbTiO_{3} −BiScO_{3} (2016)
    American Physical Society (APS)
    Details
    Publication Date: 2016-03-03
    Description: Author(s): Dipak Kumar Khatua, Lalitha K. V., Chris M. Fancher, Jacob L. Jones, and Rajeev Ranjan A comparative study of field-induced domain switching and lattice strain was carried out by in situ electric-field-dependent high-energy synchrotron x-ray diffraction on a morphotropic phase boundary (MPB) and a near-MPB rhombohedral/pseudomonoclinic composition of a high-performance piezoelectric a… [Phys. Rev. B 93, 104103] Published Wed Mar 02, 2016
    Keywords: Structure, structural phase transitions, mechanical properties, defects
    Print ISSN: 1098-0121
    Electronic ISSN: 1095-3795
    Topics: Physics
    Published by American Physical Society (APS)
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  • 3
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    Structure and properties of Fe-modified Na_{0.5}Bi_{0.5}TiO_{3} at ambient and elevated temperature (2012)
    American Physical Society (APS)
    Details
    Publication Date: 2012-01-31
    Description: Author(s): Elena Aksel, Jennifer S. Forrester, Benjamin Kowalski, Marco Deluca, Dragan Damjanovic, and Jacob L. Jones Sodium bismuth titanate (NBT) ceramics are among the most promising lead-free materials for piezoelectric applications. This work reports the crystal structure and phase evolution of NBT and Fe-modified NBT (from 0-2 at. % Fe) using synchrotron x-ray diffraction and Raman spectroscopy, at both ambien... [Phys. Rev. B 85, 024121] Published Mon Jan 30, 2012
    Keywords: Structure, structural phase transitions, mechanical properties, defects
    Print ISSN: 1098-0121
    Electronic ISSN: 1095-3795
    Topics: Physics
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  • 4
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    Domain wall and interphase boundary motion in a two-phase morphotropic phase boundary ferroelectric: Frequency dispersion and contribution to piezoelectric and dielectric properties (2012)
    American Physical Society (APS)
    Details
    Publication Date: 2012-07-13
    Description: Author(s): Jacob L. Jones, Elena Aksel, Goknur Tutuncu, Tedi-Marie Usher, Jun Chen, Xianran Xing, and Andrew J. Studer In ferroelectric materials, enhanced dielectric and piezoelectric property coefficients are found in compositions near morphotropic phase boundaries (MPBs). The material response in these compositions may be contributed by enhanced intrinsic piezoelectric distortions or increased interface motion, e... [Phys. Rev. B 86, 024104] Published Thu Jul 12, 2012
    Keywords: Structure, structural phase transitions, mechanical properties, defects
    Print ISSN: 1098-0121
    Electronic ISSN: 1095-3795
    Topics: Physics
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  • 5
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    Meiotic arrest in the mouse follicle maintained by a Gs protein in the oocyte (2002)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2002-08-24
    Description: The mammalian ovarian follicle consists of a multilayered complex of somatic cells that surround the oocyte. A signal from the follicle cells keeps the oocyte cell cycle arrested at prophase of meiosis I until luteinizing hormone from the pituitary acts on the follicle cells to release the arrest, causing meiosis to continue. Here we show that meiotic arrest can be released in mice by microinjecting the oocyte within the follicle with an antibody that inhibits the stimulatory heterotrimeric GTP-binding protein Gs. This indicates that Gs activity in the oocyte is required to maintain meiotic arrest within the ovarian follicle and suggests that the follicle may keep the cell cycle arrested by activating Gs.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Mehlmann, Lisa M -- Jones, Teresa L Z -- Jaffe, Laurinda A -- New York, N.Y. -- Science. 2002 Aug 23;297(5585):1343-5.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Physiology, University of Connecticut Health Center, Farmington, CT 06032, USA. lmehlman@neuron.uchc.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/12193786" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Antibodies/immunology ; Cells, Cultured ; Cyclic AMP/metabolism ; Female ; GTP-Binding Protein alpha Subunits, Gi-Go/immunology/physiology ; GTP-Binding Protein alpha Subunits, Gs/antagonists & ; inhibitors/immunology/*physiology ; Hypoxanthine/pharmacology ; *Meiosis ; Mice ; Oocytes/drug effects/metabolism/*physiology ; Ovarian Follicle/*physiology ; Signal Transduction
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 6
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    Stem cell self-renewal specified by JAK-STAT activation in response to a support cell cue (2001)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2001-12-26
    Description: Stem cells generate many differentiated, short-lived cell types, such as blood, skin, and sperm, throughout adult life. Stem cells maintain a long-term capacity to divide, producing daughter cells that either self-renew or initiate differentiation. Although the surrounding microenvironment or "niche" influences stem cell fate decisions, few signals that emanate from the niche to specify stem cell self-renewal have been identified. Here we demonstrate that the apical hub cells in the Drosophila testis act as a cellular niche that supports stem cell self-renewal. Hub cells express the ligand Unpaired (Upd), which activates the Janus kinase-signal transducer and activator of transcription (JAK-STAT) pathway in adjacent germ cells to specify self-renewal and continual maintenance of the germ line stem cell population.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kiger, A A -- Jones, D L -- Schulz, C -- Rogers, M B -- Fuller, M T -- GM07790-22/GM/NIGMS NIH HHS/ -- HD07493/HD/NICHD NIH HHS/ -- P01-DK53074/DK/NIDDK NIH HHS/ -- R01 GM078176/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 2001 Dec 21;294(5551):2542-5.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Developmental Biology, Stanford University School of Medicine, Stanford, CA 94305-5329, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/11752574" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell Differentiation ; Cell Division ; Cell Lineage ; Cues ; DNA-Binding Proteins/genetics/*metabolism ; Drosophila/cytology/embryology/genetics/*physiology ; Drosophila Proteins/*metabolism ; Germ Cells/*physiology ; Glycoproteins/*metabolism ; Janus Kinases ; Ligands ; Male ; Mutation ; Protein-Tyrosine Kinases/genetics/*metabolism ; STAT Transcription Factors ; Signal Transduction ; Spermatocytes/cytology/physiology ; Spermatogenesis ; Stem Cells/cytology/*physiology ; Testis/cytology/metabolism ; Trans-Activators/genetics/*metabolism ; *Transcription Factors
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 7
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    Multipotent somatic stem cells contribute to the stem cell niche in the Drosophila testis (2008)
    Nature Publishing Group (NPG)
    Details
    Publication Date: 2008-07-22
    Description: Adult stem cells reside in specialized microenvironments, or niches, that have an important role in regulating stem cell behaviour. Therefore, tight control of niche number, size and function is necessary to ensure the proper balance between stem cells and progenitor cells available for tissue homeostasis and wound repair. The stem cell niche in the Drosophila male gonad is located at the tip of the testis where germline and somatic stem cells surround the apical hub, a cluster of approximately 10-15 somatic cells that is required for stem cell self-renewal and maintenance. Here we show that somatic stem cells in the Drosophila testis contribute to both the apical hub and the somatic cyst cell lineage. The Drosophila orthologue of epithelial cadherin (DE-cadherin) is required for somatic stem cell maintenance and, consequently, the apical hub. Furthermore, our data indicate that the transcriptional repressor escargot regulates the ability of somatic cells to assume and/or maintain hub cell identity. These data highlight the dynamic relationship between stem cells and the niche and provide insight into genetic programmes that regulate niche size and function to support normal tissue homeostasis and organ regeneration throughout life.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2599791/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2599791/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Voog, Justin -- D'Alterio, Cecilia -- Jones, D Leanne -- R01 AG028092/AG/NIA NIH HHS/ -- R01 AG028092-02/AG/NIA NIH HHS/ -- England -- Nature. 2008 Aug 28;454(7208):1132-6. doi: 10.1038/nature07173. Epub 2008 Jul 20.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Laboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, California 92037, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/18641633" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cadherins/genetics/metabolism ; Cell Adhesion Molecules, Neuronal/metabolism ; Cell Lineage ; Drosophila Proteins/genetics/metabolism ; Drosophila melanogaster/*cytology/embryology/genetics ; Heat-Shock Response ; Homeostasis ; Male ; Mitosis ; Multipotent Stem Cells/*cytology/metabolism ; Regeneration ; Testis/*cytology
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Published by Nature Publishing Group (NPG)
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  • 8
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    Orbitofrontal cortex supports behavior and learning using inferred but not cached values (2012)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2012-11-20
    Description: Computational and learning theory models propose that behavioral control reflects value that is both cached (computed and stored during previous experience) and inferred (estimated on the fly on the basis of knowledge of the causal structure of the environment). The latter is thought to depend on the orbitofrontal cortex. Yet some accounts propose that the orbitofrontal cortex contributes to behavior by signaling "economic" value, regardless of the associative basis of the information. We found that the orbitofrontal cortex is critical for both value-based behavior and learning when value must be inferred but not when a cached value is sufficient. The orbitofrontal cortex is thus fundamental for accessing model-based representations of the environment to compute value rather than for signaling value per se.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592380/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592380/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Jones, Joshua L -- Esber, Guillem R -- McDannald, Michael A -- Gruber, Aaron J -- Hernandez, Alex -- Mirenzi, Aaron -- Schoenbaum, Geoffrey -- F32 DA031517/DA/NIDA NIH HHS/ -- F32-031517/PHS HHS/ -- R01 DA015718/DA/NIDA NIH HHS/ -- R01-DA015718/DA/NIDA NIH HHS/ -- ZIA DA000587-01/Intramural NIH HHS/ -- New York, N.Y. -- Science. 2012 Nov 16;338(6109):953-6. doi: 10.1126/science.1227489.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Anatomy and Neurobiology, University of Maryland School of Medicine, 20 Penn Street, Baltimore, MD 21201, USA. josh.jones@nih.gov〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23162000" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Behavior, Animal ; Conditioning (Psychology) ; Cues ; Frontal Lobe/*physiology ; *Learning ; Male ; Rats ; Rats, Inbred LEC
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 9
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    Orientation of asymmetric stem cell division by the APC tumor suppressor and centrosome (2003)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2003-09-13
    Description: Stem cell self-renewal can be specified by local signals from the surrounding microenvironment, or niche. However, the relation between the niche and the mechanisms that ensure the correct balance between stem cell self-renewal and differentiation is poorly understood. Here, we show that dividing Drosophila male germline stem cells use intracellular mechanisms involving centrosome function and cortically localized Adenomatous Polyposis Coli tumor suppressor protein to orient mitotic spindles perpendicular to the niche, ensuring a reliably asymmetric outcome in which one daughter cell remains in the niche and self-renews stem cell identity, whereas the other, displaced away, initiates differentiation.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Yamashita, Yukiko M -- Jones, D Leanne -- Fuller, Margaret T -- 1P01 DK53074/DK/NIDDK NIH HHS/ -- New York, N.Y. -- Science. 2003 Sep 12;301(5639):1547-50.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Developmental Biology, Stanford University School of Medicine, Stanford, CA 94305-5329, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/12970569" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Arabidopsis Proteins ; Cadherins/metabolism ; Calcium-Binding Proteins/*metabolism ; Cell Count ; Cell Differentiation ; *Cell Division ; Cell Polarity ; Centrosome/*physiology ; Cytoskeletal Proteins/metabolism ; Drosophila/*cytology/genetics/physiology ; Drosophila Proteins/*metabolism ; Germ Cells/cytology/*physiology ; Homeodomain Proteins/genetics/physiology ; Male ; Mutation ; Spindle Apparatus/physiology ; Stem Cells/cytology/*physiology ; Testis/cytology ; Trans-Activators/metabolism ; Tubulin/metabolism ; Tumor Suppressor Proteins/*metabolism ; beta Catenin
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 10
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    Local structure in BaTiO_{3} −BiScO_{3} dipole glasses (2016)
    American Physical Society (APS)
    Details
    Publication Date: 2016-03-15
    Description: Author(s): I. Levin, V. Krayzman, J. C. Woicik, F. Bridges, G. E. Sterbinsky, T-M. Usher, J. L. Jones, and D. Torrejon Local structures in cubic perovskite-type ( B a 0.6 B i 0.4 ) ( T i 0.6 S c 0.4 ) O 3 solid solutions that exhibit reentrant dipole glass behavior have been studied with variable-temperature x-ray/neutron total scattering, extended x-ray absorption fine structure, and electron diffraction methods. Simultaneous fitti… [Phys. Rev. B 93, 104106] Published Mon Mar 14, 2016
    Keywords: Structure, structural phase transitions, mechanical properties, defects
    Print ISSN: 1098-0121
    Electronic ISSN: 1095-3795
    Topics: Physics
    Published by American Physical Society (APS)
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