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  • 1
    Publication Date: 2019-07-13
    Description: No abstract available
    Keywords: Statistics and Probability
    Type: JSC-CN-38519 , 2017 NASA Human Research Program Investigators'' Workshop (HRP IWS 2017) Annual Meeting; Jan 23, 2017 - Jan 26, 2017; Galveston, TX; United States
    Format: application/pdf
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  • 2
    Publication Date: 2019-07-13
    Description: In 2016, the Integrated Medical Model (IMM) v4.0 underwent an extensive external review in preparation for transition to an operational status. In order to insure impartiality of the review process, the Exploration Medical Capabilities Element of NASA's Human Research Program convened the review through the Systems Review Office at NASA Goddard Space Flight Center (GSFC). The review board convened by GSFC consisted of persons from both NASA and academia with expertise in the fields of statistics, epidemiology, modeling, software development, aerospace medicine, and project management (see Figure 1). The board reviewed software and code standards, as well as evidence pedigree associated with both the input and outcomes information. The board also assesses the models verification, validation, sensitivity to parameters and ability to answer operational questions. This talk will discuss the processes for designing the review, how the review progressed and the findings from the board, as well as summarize the IMM project responses to those findings. Overall, the board found that the IMM is scientifically sound, represents a necessary, comprehensive approach to identifying medical and environmental risks facing astronauts in long duration missions and is an excellent tool for communication between engineers and physicians. The board also found IMM and its customer(s) should convene an additional review of the IMM data sources and to develop a sustainable approach to augment, peer review, and maintain the information utilized in the IMM. The board found this is critically important because medical knowledge continues to evolve. Delivery of IMM v4.0 to the Crew Health and Safety (CHS) Program will occur in the 2017. Once delivered for operational decision support, IMM v4.0 will provide CHS with additional quantitative capability in to assess astronaut medical risks and required medical capabilities to help drive down overall mission risks.
    Keywords: Statistics and Probability
    Type: GRC-E-DAA-TN38711 , 2017 NASA Human Research Program Investigators'' Workshop (HRP IWS 2016); Jan 23, 2017 - Jan 26, 2017; Galveston, TX; United States
    Format: application/pdf
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