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Hmga2 overexpression in the stroma causes PIN [Medical Sciences] (2012)

Zong, Y., Huang, J., Sankarasharma, D., Morikawa, T., Fukayama, M., Epstein, J. I., Chada, K. K., Witte, O. N.

National Academy of Sciences

In: PNAS - Proceedings of the National Academy of Sciences

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Publication Date: 2012-12-12

Description: Carcinomas most often result from the stepwise acquisition of genetic alterations within the epithelial compartment. The surrounding stroma can also play an important role in cancer initiation and progression. Given the rare frequencies of genetic events identified in cancer-associated stroma, it is likely that epigenetic changes in the tumor microenvironment...

Keywords: Significance Statements

Print ISSN: 0027-8424

Electronic ISSN: 1091-6490

Topics: Biology , Medicine , Natural Sciences in General

Published by National Academy of Sciences

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