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  • 1
    ISSN: 1612-1112
    Keywords: Column liquid chromatography ; Solid phase extraction ; Tetracycline in serum
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Summary A simple and rugged SPE method for the determination of tetracycline (TC), minocycline (MC) and demeclocycline (DCC) in porcine serum by high performance liquid chromatography (HPLC) was developed. The spiked serum sample was pretreated with 2% phosphoric acid followed by a simple and rugged solid-phase extraction procedure using the OasisTM HLB extraction cartridges. High and reproducible recoveries were obtained even though the cartridges were run dry. The extracted sample analytes were injected onto a Waters SymmetryShieldTM RP8 column. The mobile phase was a simple volatile solution containing 0.1% TFA, 2% methanol and 7% acetonitrile in Water. The antibiotics were detected at 350 nm. The calibration curves were linear from 2.0 to 25.0 μg mL−1 of TC and MC with DCC as the internal standard at a concentration of 25.0 μg mL−1. For six replicate analyses, the average recoveries of TC and MC from porcine serum sample fortified at the level of 2.5 μg mL−1 were 96.1% with 1.3% RSD and 101% with 0.54% RSD; at level of 0.5 μg mL−1 the average recoveries were 88% with 1.6% RSD and 97.8% with 1.4% RSD.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Chromatographia 30 (1990), S. 309-310 
    ISSN: 1612-1112
    Keywords: Column liquid chromatography ; Thin-layer ; GC/MS ; Aminocaproic acid in horse urine ; Solid phase extraction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Summary A rapid and efficient procedure is described for extraction and determination of aminocaproic acid in horse urine. Urine was extracted by passing through a bonded silica column (Bond-Elut). The adsorbed drug was washed free of endogenous materials before being eluted. The extract was then examined by thin-layer chromatography and HPLC. The purity of the extract was determined by gas chromatography-mass spectrometry.
    Type of Medium: Electronic Resource
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  • 3
    Publication Date: 2015-07-02
    Description: Seismic tomography has revealed very high P -wave velocities, over 8.5 km s –1 , at shallow depths, 30–100 km, beneath New Zealand. Here we study fast, high-frequency arrivals at North and South Island stations that contain additional information about the crust and mantle structure. These arrivals, which are from earthquakes within or close to the land mass, have a characteristic high-frequency precursor followed by a lower frequency, larger amplitude, main phase. Precursors were seen on at least one station from 262 of 306 candidate events; the best-recorded 76 events were analysed for wave speed, frequency content and polarization. Time–distance plots are consistent with two phases travelling at 8.38 ± 0.03 and 6.93 ± 0.05 km s –1 . The precursor has typical frequencies 4–9 Hz, the second arrival 2–4 Hz. Polarizations are off-azimuth by 30° and steeper than predicted by ray tracing through a smooth 3-D tomographic model. These results are explained by propagation through a dipping layer of order 10 km thick with seismic velocity around 8.5 km s –1 ; it is too thin to propagate frequencies below 4 Hz and waves refract from it at a steep, out-of-plane angle, explaining the anomalous polarization. Ray paths cover a region coinciding with the subducted Hikurangi Plateau; the fast layer is interpreted as the lowest section of the plateau that has transformed to eclogite, which has the same fast seismic velocity that we observe. Unlike the fast, eclogitic layers identified in subduction zones such as the Kermadecs, this layer is shallower, at 30 km, than the eclogite transformation; we therefore propose that it formed at the base of the thick plateau prior to subduction.
    Keywords: Seismology
    Print ISSN: 0956-540X
    Electronic ISSN: 1365-246X
    Topics: Geosciences
    Published by Oxford University Press on behalf of The Deutsche Geophysikalische Gesellschaft (DGG) and the Royal Astronomical Society (RAS).
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  • 4
    Publication Date: 2014-06-21
    Description: We examine seismic attenuation in the northern South Island, New Zealand, where subduction transitions to oblique collision, and plate motion occurs along multiple crustal faults overlying the subducted slab. The 3-D inversions derive Q (1/attenuation) using path attenuation t * observations for 334 distributed earthquakes recorded on permanent and temporary stations, including both velocity and acceleration records. A 2.5 s window was used for P spectra, but for S spectra longer varied lengths were selected around the predicted S arrival, using the 5–95 per cent energy integral. The Q results highlight many aspects of the structure more clearly than previously derived seismic velocity models, including a high Q slab, low Q basins, moderately low Q active fault regions, and thick lithosphere. Qs tends to be greater than Qp , except in low Q shallow upper crust. The mantle above the slab does not exhibit low Q , unlike mantle to the north beneath the volcanic region of central North Island, and is inferred to be cool and stagnant with some vertical flux of slab dehydration fluid. In the brittle crust, low Q is imaged along those faults with most recent seismicity and may be related to distributed microfractures. In the ductile crust of the greywacke terranes, zones of low Q under the faults are attributed to localized ductile deformation with high strain-rate and grain size reduction, consistent with numerical models showing the development of enhanced strain-rate zones above the strong underlying slab. In contrast the Christchurch region has no ductile lower crust and instead has high Q indicative of strong mafic rocks at 12 km depth.
    Keywords: Seismology
    Print ISSN: 0956-540X
    Electronic ISSN: 1365-246X
    Topics: Geosciences
    Published by Oxford University Press on behalf of The Deutsche Geophysikalische Gesellschaft (DGG) and the Royal Astronomical Society (RAS).
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  • 5
    Publication Date: 2015-03-15
    Description: We obtain 3-D V p and V p / V s from 8 to 70 km depth along the northern Hikurangi subduction zone, New Zealand, where the downdip limit of interseismic coupling is shallower than 15 km, and where both large shallow slow-slip events (SSEs) and small deep SSEs have been observed. Onshore–offshore marine-seismic data were incorporated, which greatly improved constraint of shallow velocities and the plate interface (PI) zone velocity structure. We also selected 2600 spatially distributed earthquakes, including seismic data from the upgraded permanent seismometer network, as well as seismic data from temporary networks deployed in 1993–1994, 2001 and 2011–2012. Our method used earthquake differential times and receiver differential times with gradational inversions. The results show extensive regions of subducted sediment, but with major variations along strike. Above the shallow PI (less than 20 km depth) and north of Gisborne there is a 70-km-long zone of high V p / V s and low V p , which is interpreted as subducted sediment with high fluid-pressure. Subducted sediment is also observed at shallower depth offshore in seismic reflection data, in the vicinity of the shallow SSEs. The SSE patch with highest slip occurs where a zone of high seismicity connects the high V p / V s upper oceanic crust to the slab upper mantle such that the oceanic crust may serve as a reservoir below the SSE slip zone and enhance dilatant strengthening. In deeper zones, where the PI is 25–45 km depth, there are northern and central zones of thick low V p , low Qp material related to underplated sediments, which are uplifting the Raukumara and Kaimanawa Ranges. Small deep (25–45 km) SSEs are related to the central deep underplated sediment zone, but no SSEs have been observed in the northern underplated zone.
    Keywords: Seismology
    Print ISSN: 0956-540X
    Electronic ISSN: 1365-246X
    Topics: Geosciences
    Published by Oxford University Press on behalf of The Deutsche Geophysikalische Gesellschaft (DGG) and the Royal Astronomical Society (RAS).
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