ISSN:
1573-4986
Schlagwort(e):
oligo-N-acetyllactosaminoglycans
;
alditols
;
WGA-agarose chromatography
;
Lewis-x
;
H-antigens
;
SSEA-1
;
in vitro biosynthesis
;
α(1-2) fucosylation
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Chemie und Pharmazie
Notizen:
Abstract Relative affinities of several fucosylated and nonfucosylated oligo-N-acetyllactosaminoglycans for immobilized wheat germ agglutinin (WGA) were studied using a chromatographic technique. α(1-3) Fucosylation of theN-acetylglucosamine unit(s) in mono- and biantennary saccharides of the Galβ1-4GlcNAc-R type strongly reduced the WGA-affinity. In contrast, α(1-2) fucosylation of the nonreducing galactose unit(s) of the saccharides did not reduce the affinity.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF00731349
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