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  • 1
    Publication Date: 1978-05-19
    Description: Barbiturate anesthetics, but not anticonvulsants, abolish the spontaneous activity of cultured spinal cord neurons; directly increase membrane conductance, an effect which is suppressed by the gamma-aminobutyric acid (GABA) antagonists picrotoxin and penicillin; and are more potent than anticonvulsants in augmenting GABA and depressing glutamate responses. Barbiturate anticonvulsants abolish picrotoxin-induced convulsive activity. These results indicate qualitative and quantitative differences between anesthetic and anticonvulsant barbiturates, which may explain their different clinical effects.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Macdonald, R L -- Barker, J L -- New York, N.Y. -- Science. 1978 May 19;200(4343):775-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/205953" target="_blank"〉PubMed〈/a〉
    Keywords: Action Potentials/drug effects ; Cells, Cultured ; Electric Conductivity ; Glutamates/pharmacology ; Membrane Potentials/drug effects ; Neurons/*drug effects ; Pentobarbital/*pharmacology ; Phenobarbital/*pharmacology ; Picrotoxin/pharmacology ; Receptors, Neurotransmitter/drug effects ; gamma-Aminobutyric Acid/pharmacology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 2
    Publication Date: 1979-09-28
    Description: Mouse spinal neurons grown in tissue culture were used to examine the membrane mechanisms of action of the peptide substance P. Two functionally distinct actions were observed, one being a rapidly desensitizing excitation, and the other being a dose-dependent, reversible depression of excitatory responses to the putative amino acid neurotransmitter glutamate. These effects on excitability suggest that substance P may play more than one role in intercellular communication in the nervous system.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Vincent, J D -- Barker, J L -- New York, N.Y. -- Science. 1979 Sep 28;205(4413):1409-12.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/224464" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell Communication ; Cells, Cultured ; Electric Conductivity ; Excitatory Amino Acid Antagonists ; Glutamates/pharmacology ; Membrane Potentials ; Mice ; Neural Inhibition ; Spinal Cord/cytology/*physiology ; Substance P/*physiology ; Synaptic Transmission
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 3
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    In:  Other Sources
    Publication Date: 2011-08-18
    Description: Preflight and in-orbit sensor and data measurements indicate that TM meets or exceeds most specifications. Measured spectral band edges meet instrument specifications in 12 out of 14 cases; there is ample dynamic range. The signal-to-noise ratio exceeds specifications, except for band 3, channel 4; and band 7 channel 7 is very noisy but still meets specifications. The modulation transfer function of channel 4, band 2, is smaller than specified. Registration errors between the primary focal plane (PFP) and the cold focal plane (CFP) are about 0.75 pixels along-scan and 0.2 pixels across scan. Forward and reverse scan discontinuities are well within ground-processing capabilities to rectify. Instrument gain variability, up to 7 percent for band 5, requires use of the internal calibration (IC) system to assure radiometric accuracy. Preliminary applications evaluation of image contents indicates that TM provides much better definition of edges than MSS.
    Keywords: SPACECRAFT INSTRUMENTATION
    Format: text
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  • 4
    Publication Date: 2011-08-19
    Description: Relative spectral response data for the Landsat-4 and Landsat-4 backup multispectral scanner subsystems (MSS), the protoflight and flight models, are presented and compared to similar data for the Landsat 1, 2 and 3 scanners. Channel (six channels per band) outputs for soil and soybean targets were simulated and compared within each band and between scanners.The principal differences between the spectral responses of the Landsat-4 scanners and previous scanners are discussed. The simulated Landsat-4 scanner outputs were 3 to 10 percent lower in the red band and 3 to 11 percent higher in the first near-IR band than previous scanners for the soybeans targets. The Landsat-4 scanners were generally more uniform from channel to channel within bands than previous scanners. In the upper-band edge of the red band of the protoflight scanner, one channel was markedly different (12 nm) from the rest. For a soybeans target, this nonuniformity resulted in a within-band difference of 6.2 percent in simulated outputs between channels.
    Keywords: SPACECRAFT INSTRUMENTATION
    Type: International Journal of Remote Sensing (ISSN 0143-1161); 6; 697-716
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  • 5
    Publication Date: 2019-07-13
    Description: A series of brief summaries of the results of individual investigations of LANDSAT 4 image data characteristics are presented. Topics are divided into MSS and TM investigations, and applications of the imaging techniques. Radiometric and geometric accuracy are emphasized.
    Keywords: GEOSCIENCES (GENERAL)
    Type: E84-10167 , NASA-CP-2326-VOL-2 , NAS 1.55:2326-VOL-2 , LANDSAT-4 Early Results Symposium; Feb 22, 1983 - Feb 24, 1983; Greenbelt, MD; United States
    Format: application/pdf
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  • 6
    Publication Date: 2019-07-13
    Description: A general overview of the LANDSAT 4 system with emphasis on the Thematic Mapper (TM) is presented. A variety of topics on the design, calibration, capabilities, and image processing techniques of the TM sensor are discussed in detail. The comparison of TM data with other MSS data is also investigated.
    Keywords: GEOSCIENCES (GENERAL)
    Type: E84-10166 , NASA-CP-2326-VOL-1 , NAS 1.55:2326-VOL-1 , LANDSAT Sci. Characterization Workshop; Dec 06, 1983|Proc. of LANDSAT-4 Early Results Symp.; Feb 22, 1983 - Feb 24, 1983; Greenbelt, MD; United States
    Format: application/pdf
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