ISSN:
1617-4623
Keywords:
nuA operon
;
Regulation
;
RNA polymerase
;
Escherichia coli
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Summary The rate of synthesis and intracellular content of the NusA protein, a transcription termination factor, were determined for wild-type and nusA and/or nusB mutants of Escherichia coli. Both the rate and content of NusA in wild-type strains were similar to that of the RNA polymerase σ subunit, a transcription initiation factor, on a molar basis, and about 30%–40% the levels of RNA polymerase ββ′ subunits. At the stationary phase of cell growth, the values increased in parallel for both transcription factors up to approximately the level of the ββ′ subunits. In nus mutants, the rate of synthesis and the content of the σ subunit were significantly increased. These observations together suggest that the two transcription factors are coordinately regulated.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00333573
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