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  • 1
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: The lifestyle of humans is rapidly changing, and, correspondingly, their needs and the current and future megatrends of the food market. It is worth mentioning (1) the preference for natural, simple, and flexible diets that drive the further expansion of plant-focused formulations, (2) the focus on food sustainability (food waste reduction), and (3) the interest in healthy eating as the basis for good health. The hectic routine and rapid urbanization in developed and developing regions, respectively, have shifted consumer preferences toward bread and baked foods, which, interestingly, are often high in sugars and are categorized as having a high glycemic index. Therefore, it is of major importance to address the technological challenges of manufacturing baked goods with high physical and sensory quality that result in positive metabolic responses. This Special Issue seeks to provide fundamental understanding in this area and novel strategies to improve the nutritional properties of baked goods, including a decrease in starch bioaccessibility, sugar reduction, increase in fiber and/or protein content, and the improvement of phytochemical bioactivity. This Special Issue will also cover studies on the physical and sensory improvements of baked goods that may provide a mechanistic understanding to minimize the loss of quality after the incorporation of nutritional-improving ingredients, such as edible byproducts, proteins, or fibers. Last but not least, studies focused on the reduction of additives (clean label) or fat and on the use of sourdough to improve the sensory properties of baked goods will also be included.
    Keywords: QH301-705.5 ; Q1-390 ; TX341-641 ; particle size ; n/a ; tempering ; maize bread ; pea ; bakery products ; antinutritional factors ; nutrition knowledge ; baking ; chia ; analytical quality ; antioxidant capacity ; protein enrichment ; mucilage ; cookie ; bakery ; cereals ; sustainability ; amylopectin ; germination ; functional foods ; maize flour ; sensory QDA ; shortening ; upcycled food by-products ; pulses ; processing ; fermentation ; sesame ; glycemic response ; sieve ; flaxseed ; Mixolab ; bio-technological processing ; ?-amylase ; TPA ; high-amylose ; baking activity ; defatted sunflower seed flour ; gluten-free ; wheat–flaxseed composite ; protein digestibility ; bran ; pseudocereals ; legume fortification ; digestion ; flour refinement ; consumer ; milk lipids ; bread ; biscuits ; air classification ; faba bean ; whole grains ; retrogradation ; intermediate wheatgrass ; lentil ; sunflower ; chickpea ; colour ; protein content ; sensory evaluation ; valorisation ; amylose ; fat replacer ; fortification ; principal component analysis ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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  • 2
    Publication Date: 2024-04-05
    Description: The brain of each animal shows specific traits that reflect its phylogenetic history and its particular lifestyle. Therefore, comparing brains is not just a mere intellectual exercise, but it helps understanding how the brain allows adaptive behavioural strategies to face an ever-changing world and how this complex organ has evolved during phylogeny, giving rise to complex mental processes in humans and other animals. These questions attracted scientists since the times of Santiago Ramon y Cajal one of the founders of comparative neurobiology. In the last decade, this discipline has undergone a true revolution due to the analysis of expression patterns of morphogenetic genes in embryos of different animals. The papers of this e-book are good examples of modern comparative neurobiology, which mainly focuses on the following four Grand Questions: a) How are different brains built during ontogeny? b) What is the anatomical organization of mature brains and how can they be compared? c) How do brains work to accomplish their function of ensuring survival and, ultimately, reproductive success? d) How have brains evolved during phylogeny? The title of this e-book, Adaptive Function and Brain Evolution, stresses the importance of comparative studies to understand brain function and, the reverse, of considering brain function to properly understand brain evolution. These issues should be taken into account when using animals in the research of mental function and dysfunction, and are fundamental to understand the origins of the human mind.
    Keywords: RC321-571 ; Q1-390 ; comparative neurobiology ; brain evolution ; phylogeny ; ontogeny ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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  • 3
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    Frontiers Media SA
    Publication Date: 2024-04-05
    Description: Could we understand, in biological terms, the unique and fantastic capabilities of the human brain to both create and enjoy art? In the past decade neuroscience has made a huge leap in developing experimental techniques as well as theoretical frameworks for studying emergent properties following the activity of large neuronal networks. These methods, including MEG, fMRI, sophisticated data analysis approaches and behavioral methods, are increasingly being used in many labs worldwide, with the goal to explore brain mechanisms corresponding to the artistic experience. The 37 articles composing this unique Frontiers Research Topic bring together experimental and theoretical research, linking state-of-the-art knowledge about the brain with the phenomena of Art. It covers a broad scope of topics, contributed by world-renowned experts in vision, audition, somato-sensation, movement, and cinema. Importantly, as we felt that a dialog among artists and scientists is essential and fruitful, we invited a few artists to contribute their insights, as well as their art. Joan Miró said that “art is the search for the alphabet of the mind.” This volume reflects the state of the art search to understand neurobiological alphabet of the Arts. We hope that the wide range of articles in this volume will be highly attractive to brain researchers, artists and the community at large.
    Keywords: RC321-571 ; Q1-390 ; emotion ; neuroesthetics ; performing-arts ; creativity ; perception ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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  • 4
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: The future of the precious metals is shiny and resistant. Although expensive and potentially replaceable by transition metal catalysts, precious metal implementation in research and industry shows potential. These metals catalyze oxidation and hydrogenation due to their dissociative behavior toward hydrogen and oxygen, dehydrogenation, isomerization, and aromatization, etc. The precious metal catalysts, especially platinum-based catalysts, are involved in a variety of industrial processes. Examples include Pt–Rh gauze for nitric acid production, the Pt/Al2O3 catalyst for cyclohexane and propylene production, and Pd/Al2O3 catalysts for petrochemical hydropurification reactions, etc. A quick search of the number of published articles in the last five years containing a combination of corresponding “metals” (Pt, Pd, Ru, Rh and Au) and “catalysts” as keywords indicates the importance of the Pt catalysts, but also the continuous increase in the contribution of Pd and Au. This Special Issue reveals the importance of precious metals in catalysis and focuses on mono- and bi-metallic formulations of any supported precious metals and their promotional catalytic effect of other transition metals. The application of precious metals in diverse reactions, either homogeneous or heterogeneous, and studies of the preparation, characterization, and applications of the supported precious metal catalysts, are presented.
    Keywords: QD1-999 ; QD146-197 ; Q1-390 ; sustainable ammonia synthesis ; Pt3Sn alloy ; alkenols ; n/a ; PtSn alloy ; propane dehydrogenation ; chelate ; photodegradation ; gold nanoparticles ; photochemical ; alkynols ; triple bond electron charge ; palladium catalyst ; Pt/Al2O3 ; 2-methyl-3-butyn-2-ol ; hydrogen storage ; X-ray crystallography ; ruthenium ; platinum dispersion ; gold catalysts ; reduction temperature ; DOC ; palladium ; renewable hydrogen ; 1-propanol ; 4-hydroxyproline ; glycerol ; 2-?-benzylproline ; proline ; hydrogen bonding ; oxidative coupling ; glucose oxidation ; stabilizing agent ; titania ; 4-fluoroproline ; turnover frequency ; porous carbons ; Pt–Sn/Al2O3 ; P25@Pd ; catalyst synthesis ; 2-propanol ; amino acid ; azetidine ; precious metals ; clay ; gas phase hydrogenation ; CNTs ; 3-butyn-2-ol ; Pd/Al2O3 ; heterogeneous enantioselective hydrogenation ; XPS ; microwave ; caesium ; perovskite ; CO oxidation ; Au–TiO2 ; dodecahydro-N-ethylcarbazole ; phenol photo-degradation ; pipecolinic acid ; 3-butyn-1-ol ; acetophenone ; drying ; palladium catalysts ; N-methylproline ; dehydrogenation ; PVA ; aging ; hydrodechlorination ; hydrogenolysis ; dispersion ; direct reduction ; core-shell ; thema EDItEUR::P Mathematics and Science::PN Chemistry
    Language: English
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  • 5
    Publication Date: 2024-04-05
    Description: In the mid-sixties, the discovery by Altman and co-workers of neurogenesis in the adult brain changed the previous conception of the immutability of this organ during adulthood sustained among others by Cajal. This discovery was ignored up to eighty’s when Nottebohm demonstrated neurogenesis in birds. Subsequently, two main neurogenic zones were characterized: the subventricular zone of the lateral ventricle and the subgranular layer of the dentate gyrus. Half century later, the exact role of new neurons in the adult brain is not completely understand. This book is composed by a number of articles by leaders in the filed covering from an historic perspective to potential therapeutic opportunities.
    Keywords: RC321-571 ; Q1-390 ; Stroke ; Dopamine ; Exercise ; Epilepsy ; Alzheimer ; glia ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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  • 6
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: The emergence of marine and freshwater toxins in geographical areas where they have never been reported before is a concern due to the considerable impact on (sea)food contamination, and consequently, on public health. Several groups of marine biotoxins, in particular tetrodotoxins, ciguatoxins, and palytoxins, are included among the relevant marine biotoxins that have recently emerged in several coastal areas. A similar situation has been observed in freshwater, where cyanobacterial toxins, such as microcystins, could end up in unexpected areas such as the estuaries where shellfish are cultivated. Climate change and the increased availability of nutrients have been considered as the key factors in the expansion of all of these toxins into new areas; however, this could also be due to more intense biological invasions, more sensitive analytical methods, or perhaps even an increased scientific interest in these natural contaminations. The incidences of human intoxications due to the consumption of seafood contaminated with these toxins have made their study an important task to accomplish in order to protect human health. This Special Issue has a focus on a wide variety of emerging biotoxin classes and techniques to identify and quantify them.
    Keywords: QH301-705.5 ; Q1-390 ; n/a ; C-CTX-1 ; non-targeted analysis ; ciguatera fish poisoning ; suspects screening ; neurodegeneration ; adaptation ; LC-HRMS ; paralytic shellfish toxins ; LC-MS/MS ; animal toxins ; identification ; method characterization ; caribbean ciguatoxins ; oral toxicity ; water flea ; quorum sensing ; eutrophication ; beta-methyl-amino-l-alanine ; dynamics simulation ; thermal water ; spent medium ; Microcystis ; Gambierdiscus ; gambierdiscus ; whole genome sequencing ; palytoxin ; conotoxin ; ovatoxins ; cyanobacterial toxin ; BMAA ; Ciguatera fish poisoning ; Rastrineobola argentea ; calcium-activated K+ ion channel ; toxicity equivalence factor ; NMR spectroscopy ; N2a ; PPIA ; marine biotoxins ; Daphnia magna ; ELISA ; disulfide-rich peptide ; food chain ; ShK-like peptide ; voltage-gated K+ ion channel ; targeted analysis ; Chinese yellow catfish ; marine ; macaronesia ; neuroblastoma bioassay ; marine toxins ; acute toxicity ; algal–bacterial relationship ; mass spectrometry ; tetrodotoxins ; saxitoxin ; toxicology ; cationization ; seafood safety ; evolution ; cyanotoxins ; toxin genes ; zoantharian ; spatial variability ; dopaminergic neurons ; tetrodotoxin ; bivalve mollusks ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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  • 7
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: The characterization of peptides and proteins is central to understanding their function and expression in biological matrices. Moreover, these macromolecules are important biomarkers of many human diseases. In recent years, the performance of separation techniques based on electromigration have significantly increased. The development of microdevices has reduced sample consumption and waste production while high-sensitivity detectors, such as mass spectrometry (MS) or laser-induced fluorescence (LIF), have significantly improved with regards to separation efficiency and detection limits. All of these advancements have led to appreciably enlarged fields of application. Nowadays, a multitude of studies using separation techniques based on electromigration to study proteins and peptides from numerous real matrices are available in the literature. This Special Issue covers the most recent knowledge and advances in the study of peptides and proteins using several electrophoresis techniques, as well as the characterization of relevant proteins and peptides in application areas such as clinical studies, functional foods, and toxicology.
    Keywords: QD1-999 ; Q1-390 ; QD450-801 ; seed phosphoproteomics ; LC-ESI-MS ; purity ; transferrin ; CE-LIF ; enzyme assay ; thioglucosidase ; capillary electrophoresis ; venom composition ; immunoassay ; fluorescence ; seed proteomics ; SEC-HPLC ; desulfo-sinigrin ; metalloproteins ; seed quality traits ; seed glycoproteomics ; proteomics ; sulfatase ; on-gel detection ; non-covalent binding ; Naja ashei ; myrosinase ; SDS-PAGE ; carbon dots ; 2-D electrophoresis ; fragment ; rhIL-12 ; seed molecular breeding ; chip-based CE-LIF assay ; thema EDItEUR::P Mathematics and Science::PN Chemistry
    Language: English
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  • 8
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Allohexaploid bread wheat and diploid barley are two of the most cultivated crops in the world. This book reports novel research and reviews concerning the use of modern technologies to understand the molecular bases for wheat and barley improvement. The contributions published in this book illustrate research advances in wheat and barley knowledge using modern molecular techniques. These molecular approaches cover genomic, transcriptomic, proteomic, and phenomic levels, together with new tools for gene identification and the development of novel molecular markers. Overall, the contributions for this book lead to a further understanding of regulatory systems in order to improve wheat and barley performance.
    Keywords: QH301-705.5 ; Q1-390 ; n/a ; biotechnology ; transgene ; Aegilops tauschii ; antioxidant enzymes ; aquaporin ; molecular marker ; Kompetitive Allele Specific PCR (KASP) ; transgenic wheat ; purple acid phosphatase phytase ; genome editing ; genes ; resistance ; genome assembly ; germination ; protein two-dimensional electrophoresis ; 1 ; disease resistance ; Thinopyrum ; plant ; oligo probe ; optical mapping ; genetic biofortification ; breeding ; population structure ; marker-assisted selection ; crops ; hybrid necrosis ; PAPhy ; Triticeae ; wheat ; Barley ; genome stability ; CRISPR ; powdery mildew ; RNA editing ; bread wheat ; allohexaploid ; nucleus ; chromatin ; introgression ; favorable alleles ; genetic engineering ; Tunisian landraces ; barely ; Pm40 ; Blumeria graminis f. sp. tritici ; Transcriptional dynamics ; Lr42 ; Triticum durum ; histochemical analysis ; molecular mapping ; ribosomal DNA ; 12-oxophytodienoate reductase ; small segment translocation ; HIGS ; Powdery mildew ; abiotic stress ; phytase ; RNA-seq ; Bulked segregant analysis-RNA-Seq (BSR-Seq) ; grain ; DArTseq technology ; center of diversity ; mature grain phytase activity (MGPA) ; cereals ; Grain development ; hybrid ; homoeolog ; 3D-FISH ; jasmonates ; Single nucleotide polymorphism (SNP) ; genetic diversity ; ND-FISH ; durum wheat ; protease ; transpiration ; TdPIP2 ; cereal cyst nematodes ; mass spectrometry ; 6R ; Landrace ; marker-trait associations ; BAC ; chromosome ; barley ; freezing tolerance ; KASP markers ; Triticum aestivum ; rye ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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  • 9
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: The development of new plant varieties is a long and tedious process involving the generation of large seedling populations for the selection of the best individuals. While the ability of breeders to generate large populations is almost unlimited, the selection of these seedlings is the main factor limiting the generation of new cultivars. Molecular studies for the development of marker-assisted selection (MAS) strategies are particularly useful when the evaluation of the character is expensive, time-consuming, or with long juvenile periods. The papers published in the Special Issue “Plant Genetics and Molecular Breeding” report highly novel results and testable new models for the integrative analysis of genetic (phenotyping and transmission of agronomic characters), physiology (flowering, ripening, organ development), genomic (DNA regions responsible for the different agronomic characters), transcriptomic (gene expression analysis of the characters), proteomic (proteins and enzymes involved in the expression of the characters), metabolomic (secondary metabolites), and epigenetic (DNA methylation and histone modifications) approaches for the development of new MAS strategies. These molecular approaches together with an increasingly accurate phenotyping will facilitate the breeding of new climate-resilient varieties resistant to abiotic and biotic stress, with suitable productivity and quality, to extend the adaptation and viability of the current varieties.
    Keywords: QH301-705.5 ; Q1-390 ; n/a ; GA2ox7 ; cabbage ; OsGPAT3 ; oleic acid ; OsCDPK1 ; nutrient use efficiency ; stem borer ; yellow-green-leaf mutant ; branching ; epigenetics ; NPK fertilizers ; particle bombardment ; stress tolerance ; overexpression ; glycine ; heat-stress ; bulk segregant RNA-seq ; Prunus ; protein-protein interaction ; AdRAP2.3 ; plant architecture ; waterlogging stress ; genes ; Cucumis sativus L. ; Flower color ; resistance ; Tobacco ; gynomonoecy ; drought stress ; Brassica oleracea ; starch biosynthesis ; Overexpression ; WUS ; agronomic traits ; Ghd7 ; the modified MutMap method ; cry2A gene ; light-induced ; gene expression ; breeding ; Heterodera schachtii ; ABA ; Green tissue-specific expression ; subcellular localization ; squamosa promoter binding protein-like ; transcriptome ; FAD2 ; As3+ stress ; metallothionein ; flowering ; bisulfite sequencing ; tomato ; quantitative trait loci ; Promoter ; marker–trait association ; DEGs ; cytoplasmic male sterile ; Rosa rugosa ; MADS transcription factor ; yield ; P. suffruticosa ; CYC2 ; common wild rice ; Actinidia deliciosa ; gene-by-gene interaction ; Aechmea fasciata ; hybrid rice ; soybean ; R2R3-MYB ; bread wheat ; BRANCHED1 (BRC1) ; linoleic acid ; differentially expressed genes ; complex traits ; transgenic chrysanthemum ; D-genome ; Brassica ; candidate gene ; SmJMT ; gene expression pattern ; RNA-Seq ; candidate genes ; leaf shape ; Brassica napus ; recombination-suppressed region ; anthocyanin ; WRKY transcription factor ; Idesia polycarpa var ; single nucleotide polymorphism ; bud abortion ; QTL ; reproductive organ ; transient overexpression ; Elongated Internode (EI) ; sugarcane ; abiotic stress ; Oryza sativa L. ; RrGT2 gene ; Hd1 ; cZR3 ; cytoplasmic male sterility (CMS) ; seed development ; tapetum ; near-isogenic line (NIL) ; phytohormones ; TCP transcription factor ; pollen accumulation ; Anthocyanin ; WRKY ; quantitative trait loci (QTLs) ; salt stress ; floral scent ; sucrose ; Ogura-CMS ; root traits ; endosperm development ; Zea mays L. ; sesame ; Bryum argenteum ; AP2/ERF genes ; transcriptional regulation ; WB1 ; haplotype block ; broccoli ; agronomic efficiency ; durum wheat ; gene pyramiding ; Oryza sativa ; genetics ; flowering time ; Cicer arietinum ; Hs1pro-1 ; endosperm appearance ; phenolic acids ; anther wall ; bromeliad ; genomics ; transgenic ; DgWRKY2 ; Clone ; yield trait ; flower symmetry ; partial factor productivity ; rice ; molecular breeding ; genotyping-by-sequencing ; Chimonanthus praecox ; nectary ; Salvia miltiorrhiza ; pollen development ; regulation ; ZmES22 ; genome-wide association study ; VIGS ; iTRAQ ; genome-wide association study (GWAS) ; ethylene-responsive factor ; starch ; molecular markers ; rice quality ; Chrysanthemum morifolium ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 10
    Publication Date: 2022-01-31
    Description: The regulated secretory pathway is a hallmark of neuroendocrine cells. This process comprises many sequential steps, which include ER-associated protein synthesis, post-translational modification of proteins in the Golgi complex, sorting and packing of secretory proteins into carrier granules, cytoskeleton-based granule transport towards the plasma membrane and tethering, docking and fusion of granules with specialized releasing zones. Each stage is subjected to a rigorous regulation by a plethora of factors that function in a spatially and temporarily coordinated fashion. Much effort has been devoted to characterize the precise role of the regulatory proteins participating in the different steps of this process and to identify new factors in order to obtain a unifying picture of the secretory pathway. In spite of this and given the enormous complexity of the process, certain stages are not fully understood yet and many players remain to be identified. The aim of this Research Topic is to gather review articles and original research papers on the molecular mechanisms that govern and ensure the correct release of neuropeptides.
    Keywords: RC648-665 ; R5-920 ; RC321-571 ; Q1-390 ; Neuroendocrine Cells ; regulated exocytosis ; Endocytosis ; secretion ; large dense core vesicles ; Membrane trafficking ; super-resolution microscopy
    Language: English
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