ISSN:
0021-8995
Keywords:
Chemistry
;
Polymer and Materials Science
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
,
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
,
Physics
Notes:
Chloromethylstyrene-ethylene glycol dimethacrylate (EGDMA) copolymer beads (PCMS) and dimethylaminomethylstyrene-EGDMA copolymer (PDAMS) were synthesized by suspension polymerization as noble polymer matrices. The chemical and physical properties of the quaternized resins (PCMS-Q and PDAMS-Q) were approximately equal. The characteristics of both resins were examined by high-performance liquid chromatography using columns packed with the resins. These resins served as conventional anion-exchange resins for small organic anions, but indicated markedly different retention for large molecular anions, namely, PDAMS-Q retained proteins having a negative net charge, but PCMS-Q did not. It was suggested that the chemical and physical structures on the external surfaces of ion exchangers are very important in ion-exchange chromatography of proteins.
Additional Material:
4 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/app.1992.070460318
Permalink
