ISSN:
0894-3230
Keywords:
Organic Chemistry
;
Physical Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
,
Physics
Notes:
Transition metal ions are effective catalysts of the hydrolytic cleavage of amino acid esters and their effects can be enhanced and properly directed when they are chelated to functionalized ligands. The resulting metallocatalysts are attracting increasing attention and the systems so far investigated are briefly reviewed. Particular emphasis is given to supramolecular systems which may add to the metallocatalysts the benefits of the cooperativity, set upon convergent non-covalent interactions of their components, needed for substrate recognition. The results obtained with metallomicellar aggregates and molecular metalloreceptors, with particular reference to those studied in the authors' laboratory, are reported in more detail. In the case of loosely structured metallomicelles, remarkable accelerations and, generally, modest selectivities have been observed; less spectacular kinetic effects, but promising substrate selectivity, have been obtained with structurally well defined metalloreceptors.
Additional Material:
2 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/poc.610051002
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