ISSN:
0268-2605
Keywords:
organosilicon complexes
;
Schiff base ligands
;
benzethiazolines
;
antifungal
;
antibacterial and antifertility activities
;
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Synthetic, structural and biological aspects of trigonal-bipyramidal, Me2S(N - S)CI and octahedral, Me2Si(N - S)2 types of diorganosilicon(IV) complexes of heterocyclic benzothiazolines (N - SH) are described. The complexes were characterized by elemental analysis, molecular weight determination, conductance measurements and electronic, infrared, 1H and 13C NMR spectroscopic studies. Some ligands and their corresponding dimethylsilicon(IV) complexes have been tested for their effects on several pathogenic fungi and bacteria and found to be quite active in this respect. Antifertility activity in male mice of some representative ligands and their silicon complexes was also evaluated and discussed.
Additional Material:
6 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/aoc.590090206
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