ISSN:
0018-019X
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Amphetamine (I) reacts spontaneously at room temperature with carbon disulfide to form (1-phenyl-isopropyl)-isothiocyanate, which was identified by UV.-, IR.- and mass spectrometry. This reaction is used for the analytical determination of I by gas chromatography. The characteristic peak shift which occurs after addition of carbon disulfide differentiates I from N-methylamphetamine (II). The method is applied to urine analysis of I and II (which partially metabolizes to I) and might be useful in doping control.
Additional Material:
2 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/hlca.19670500319
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