ISSN:
0021-8383
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Synthesis of N-Maleoyl-aminoacids and -peptidesN-Maleoyl-aminoacid-N′-hydroxysuccinimidesters 3 or N-maleoyl-aminobenzoic acids 5 are synthesized from N-maleyl-aminoacids 1 on different ways. N-maleoyl-aminobenzoic-4-nitro-phenyl-,-2-nitro-phenyl-or 2,4-dinitro-phenylesters 6, 7 and 8 will be obtained from 1 or 5. o-Mercapto-aniline, thiourea or cysteine react with 5 to benzothiazines 9, thiazolidines 10 and 1,4-thiazines 11. from 5 the peptides 12 are yielded. The pentapeptide 13 are formed from 12 by addition of glutathione.
Additional Material:
3 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/prac.19853270511
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